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Mucosal and systemic immunogenicity of a recombinant, non-ADP-ribosylating pertussis toxin: effects of formaldehyde treatment.
Cropley I, Douce G, Roberts M, Chatfield S, Pizza M, Marsili I, Rappuoli R, Dougan G. Cropley I, et al. Vaccine. 1995 Dec;13(17):1643-8. doi: 10.1016/0264-410x(95)00134-m. Vaccine. 1995. PMID: 8719514
However, i.n. immunization with HFT toxin failed to induce a local IgA response and elicited a much diminished anti-toxin response in the serum. ...In addition, i.n. immunization with native PT-9K/129G induced low but detectable levels of toxin neutralizing antibodi …
However, i.n. immunization with HFT toxin failed to induce a local IgA response and elicited a much diminished anti-toxin response in …
A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins.
Roberts M, Bacon A, Rappuoli R, Pizza M, Cropley I, Douce G, Dougan G, Marinaro M, McGhee J, Chatfield S. Roberts M, et al. Infect Immun. 1995 Jun;63(6):2100-8. doi: 10.1128/IAI.63.6.2100-2108.1995. Infect Immun. 1995. PMID: 7768587 Free PMC article.
High levels of IgA antibodies were present in nasal lavage fluid from mice immunized i.n. with Frg C plus PT-9K/129G, PTX, or CT but not in that from mice given Frg C alone i.n. or parenterally. ...A single i.n. dose of Frg C plus either PT-9K/129G or PTX (wi …
High levels of IgA antibodies were present in nasal lavage fluid from mice immunized i.n. with Frg C plus PT-9K/129G, PTX, or CT but …
Expanded blood borne virus testing in a tuberculosis clinic. A cost and yield analysis.
Sewell J, Capocci S, Johnson J, Solamalai A, Hopkins S, Cropley I, Webster DP, Lipman M. Sewell J, et al. J Infect. 2015 Apr;70(4):317-23. doi: 10.1016/j.jinf.2014.10.014. Epub 2014 Nov 5. J Infect. 2015. PMID: 25452045
Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants.
Douce G, Turcotte C, Cropley I, Roberts M, Pizza M, Domenghini M, Rappuoli R, Dougan G. Douce G, et al. Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1644-8. doi: 10.1073/pnas.92.5.1644. Proc Natl Acad Sci U S A. 1995. PMID: 7878032 Free PMC article.
Kinetics and toxicity of liposomal and conventional amikacin in a patient with multidrug-resistant tuberculosis.
Whitehead TC, Lovering AM, Cropley IM, Wade P, Davidson RN. Whitehead TC, et al. Eur J Clin Microbiol Infect Dis. 1998 Nov;17(11):794-7. doi: 10.1007/s100960050189. Eur J Clin Microbiol Infect Dis. 1998. PMID: 9923523
The development of oral vaccines based on live attenuated Salmonella strains.
Chatfield S, Roberts M, Londono P, Cropley I, Douce G, Dougan G. Chatfield S, et al. FEMS Immunol Med Microbiol. 1993 Jun;7(1):1-7. doi: 10.1111/j.1574-695X.1993.tb00374.x. FEMS Immunol Med Microbiol. 1993. PMID: 8364518 Review.
Virological and immunological effects of short-course antiretroviral therapy in primary HIV infection.
Fidler S, Oxenius A, Brady M, Clarke J, Cropley I, Babiker A, Zhang HT, Price D, Phillips R, Weber J. Fidler S, et al. AIDS. 2002 Oct 18;16(15):2049-54. doi: 10.1097/00002030-200210180-00010. AIDS. 2002. PMID: 12370504 Clinical Trial.
The value of "inform and advise" guidance in a case of extensive tuberculosis transmission.
Kumar K, Shorten RJ, Capocci S, Solamalai A, Goodburn A, Cropley I, McHugh TD, Lipman M. Kumar K, et al. J Infect. 2013 Aug;67(2):158-60. doi: 10.1016/j.jinf.2013.04.005. Epub 2013 Apr 13. J Infect. 2013. PMID: 23588105 No abstract available.
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