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Genome-Wide Profiling of DNA Double-Strand Breaks by the BLESS and BLISS Methods.
Mirzazadeh R, Kallas T, Bienko M, Crosetto N. Mirzazadeh R, et al. Among authors: crosetto n. Methods Mol Biol. 2018;1672:167-194. doi: 10.1007/978-1-4939-7306-4_14. Methods Mol Biol. 2018. PMID: 29043625
We developed Breaks Labeling, Enrichment on Streptavidin, and Sequencing (BLESS), which was the first method for direct labeling of DSBs in situ followed by their genome-wide mapping at nucleotide resolution (Crosetto et al., Nat Methods 10:361-365, 2013). ...
We developed Breaks Labeling, Enrichment on Streptavidin, and Sequencing (BLESS), which was the first method for direct labeling of DSBs in …
Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing.
Crosetto N, Mitra A, Silva MJ, Bienko M, Dojer N, Wang Q, Karaca E, Chiarle R, Skrzypczak M, Ginalski K, Pasero P, Rowicka M, Dikic I. Crosetto N, et al. Nat Methods. 2013 Apr;10(4):361-5. doi: 10.1038/nmeth.2408. Epub 2013 Mar 17. Nat Methods. 2013. PMID: 23503052 Free PMC article.
Spatially resolved transcriptomics and beyond.
Crosetto N, Bienko M, van Oudenaarden A. Crosetto N, et al. Nat Rev Genet. 2015 Jan;16(1):57-66. doi: 10.1038/nrg3832. Epub 2014 Dec 2. Nat Rev Genet. 2015. PMID: 25446315 Review.
Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction.
Mooijman D, Dey SS, Boisset JC, Crosetto N, van Oudenaarden A. Mooijman D, et al. Among authors: crosetto n. Nat Biotechnol. 2016 Aug;34(8):852-6. doi: 10.1038/nbt.3598. Epub 2016 Jun 27. Nat Biotechnol. 2016. PMID: 27347753
Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.
Shi W, Vu T, Boucher D, Biernacka A, Nde J, Pandita RK, Straube J, Boyle GM, Al-Ejeh F, Nag P, Jeffery J, Harris JL, Bain AL, Grzelak M, Skrzypczak M, Mitra A, Dojer N, Crosetto N, Cloonan N, Becherel OJ, Finnie J, Skaar JR, Walkley CR, Pandita TK, Rowicka M, Ginalski K, Lane SW, Khanna KK. Shi W, et al. Among authors: crosetto n. Blood. 2017 May 4;129(18):2479-2492. doi: 10.1182/blood-2016-06-725093. Epub 2017 Mar 7. Blood. 2017. PMID: 28270450 Free PMC article.
BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks.
Yan WX, Mirzazadeh R, Garnerone S, Scott D, Schneider MW, Kallas T, Custodio J, Wernersson E, Li Y, Gao L, Federova Y, Zetsche B, Zhang F, Bienko M, Crosetto N. Yan WX, et al. Among authors: crosetto n. Nat Commun. 2017 May 12;8:15058. doi: 10.1038/ncomms15058. Nat Commun. 2017. PMID: 28497783 Free PMC article.
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks.
Iannelli F, Galbiati A, Capozzo I, Nguyen Q, Magnuson B, Michelini F, D'Alessandro G, Cabrini M, Roncador M, Francia S, Crosetto N, Ljungman M, Carninci P, d'Adda di Fagagna F. Iannelli F, et al. Among authors: crosetto n. Nat Commun. 2017 May 31;8:15656. doi: 10.1038/ncomms15656. Nat Commun. 2017. PMID: 28561034 Free PMC article.
An Application-Directed, Versatile DNA FISH Platform for Research and Diagnostics.
Gelali E, Custodio J, Girelli G, Wernersson E, Crosetto N, Bienko M. Gelali E, et al. Among authors: crosetto n. Methods Mol Biol. 2018;1766:303-333. doi: 10.1007/978-1-4939-7768-0_17. Methods Mol Biol. 2018. PMID: 29605860
Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing.
Kim C, Gao R, Sei E, Brandt R, Hartman J, Hatschek T, Crosetto N, Foukakis T, Navin NE. Kim C, et al. Among authors: crosetto n. Cell. 2018 May 3;173(4):879-893.e13. doi: 10.1016/j.cell.2018.03.041. Epub 2018 Apr 19. Cell. 2018. PMID: 29681456 Free PMC article.
i-BLESS is an ultra-sensitive method for detection of DNA double-strand breaks.
Biernacka A, Zhu Y, Skrzypczak M, Forey R, Pardo B, Grzelak M, Nde J, Mitra A, Kudlicki A, Crosetto N, Pasero P, Rowicka M, Ginalski K. Biernacka A, et al. Among authors: crosetto n. Commun Biol. 2018 Oct 31;1:181. doi: 10.1038/s42003-018-0165-9. eCollection 2018. Commun Biol. 2018. PMID: 30393778 Free PMC article.
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