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BIN1 favors the spreading of Tau via extracellular vesicles.
Crotti A, Sait HR, McAvoy KM, Estrada K, Ergun A, Szak S, Marsh G, Jandreski L, Peterson M, Reynolds TL, Dalkilic-Liddle I, Cameron A, Cahir-McFarland E, Ransohoff RM. Crotti A, et al. Sci Rep. 2019 Jul 1;9(1):9477. doi: 10.1038/s41598-019-45676-0. Sci Rep. 2019. PMID: 31263146 Free PMC article.
Cell-autonomous and non-cell autonomous effects of neuronal BIN1 loss in vivo.
McAvoy KM, Rajamohamed Sait H, Marsh G, Peterson M, Reynolds TL, Gagnon J, Geisler S, Leach P, Roberts C, Cahir-McFarland E, Ransohoff RM, Crotti A. McAvoy KM, et al. Among authors: crotti a. PLoS One. 2019 Aug 13;14(8):e0220125. doi: 10.1371/journal.pone.0220125. eCollection 2019. PLoS One. 2019. PMID: 31408457 Free PMC article.
BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology.
Taga M, Petyuk VA, White C, Marsh G, Ma Y, Klein HU, Connor SM, Kroshilina A, Yung CJ, Khairallah A, Olah M, Schneider J, Karhohs K, Carpenter AE, Ransohoff R, Bennett DA, Crotti A, Bradshaw EM, De Jager PL. Taga M, et al. Among authors: crotti a. Mol Neurodegener. 2020 Jul 29;15(1):44. doi: 10.1186/s13024-020-00387-3. Mol Neurodegener. 2020. PMID: 32727516 Free PMC article.
Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.
Escoubet-Lozach L, Benner C, Kaikkonen MU, Lozach J, Heinz S, Spann NJ, Crotti A, Stender J, Ghisletti S, Reichart D, Cheng CS, Luna R, Ludka C, Sasik R, Garcia-Bassets I, Hoffmann A, Subramaniam S, Hardiman G, Rosenfeld MG, Glass CK. Escoubet-Lozach L, et al. Among authors: crotti a. PLoS Genet. 2011 Dec;7(12):e1002401. doi: 10.1371/journal.pgen.1002401. Epub 2011 Dec 8. PLoS Genet. 2011. PMID: 22174696 Free PMC article.
25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.
Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH Jr, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK. Shibata N, et al. Among authors: crotti a. J Biol Chem. 2013 Dec 13;288(50):35812-23. doi: 10.1074/jbc.M113.519637. Epub 2013 Nov 4. J Biol Chem. 2013. PMID: 24189069 Free PMC article.
114 results