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39 results
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Crosstalk and signaling switches in mitogen-activated protein kinase cascades.
Fey D, Croucher DR, Kolch W, Kholodenko BN. Fey D, et al. Among authors: croucher dr. Front Physiol. 2012 Sep 18;3:355. doi: 10.3389/fphys.2012.00355. eCollection 2012. Front Physiol. 2012. PMID: 23060802 Free PMC article.
Signalling by protein phosphatases and drug development: a systems-centred view.
Nguyen LK, Matallanas D, Croucher DR, von Kriegsheim A, Kholodenko BN. Nguyen LK, et al. Among authors: croucher dr. FEBS J. 2013 Jan;280(2):751-65. doi: 10.1111/j.1742-4658.2012.08522.x. Epub 2012 Mar 14. FEBS J. 2013. PMID: 22340367 Free PMC article. Review.
Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients.
Fey D, Halasz M, Dreidax D, Kennedy SP, Hastings JF, Rauch N, Munoz AG, Pilkington R, Fischer M, Westermann F, Kolch W, Kholodenko BN, Croucher DR. Fey D, et al. Among authors: croucher dr. Sci Signal. 2015 Dec 22;8(408):ra130. doi: 10.1126/scisignal.aab0990. Sci Signal. 2015. PMID: 26696630
PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells.
Rogers S, Fey D, McCloy RA, Parker BL, Mitchell NJ, Payne RJ, Daly RJ, James DE, Caldon CE, Watkins DN, Croucher DR, Burgess A. Rogers S, et al. Among authors: croucher dr. J Cell Sci. 2016 Apr 1;129(7):1340-54. doi: 10.1242/jcs.179754. Epub 2016 Feb 12. J Cell Sci. 2016. PMID: 26872783 Free PMC article.
Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers.
Croucher DR, Iconomou M, Hastings JF, Kennedy SP, Han JZ, Shearer RF, McKenna J, Wan A, Lau J, Aparicio S, Saunders DN. Croucher DR, et al. Sci Signal. 2016 Jul 12;9(436):ra69. doi: 10.1126/scisignal.aaf0793. Sci Signal. 2016. PMID: 27405979
The Under-Appreciated Promiscuity of the Epidermal Growth Factor Receptor Family.
Kennedy SP, Hastings JF, Han JZ, Croucher DR. Kennedy SP, et al. Among authors: croucher dr. Front Cell Dev Biol. 2016 Aug 22;4:88. doi: 10.3389/fcell.2016.00088. eCollection 2016. Front Cell Dev Biol. 2016. PMID: 27597943 Free PMC article. Review.
Axl-EGFR receptor tyrosine kinase hetero-interaction provides EGFR with access to pro-invasive signalling in cancer cells.
Vouri M, Croucher DR, Kennedy SP, An Q, Pilkington GJ, Hafizi S. Vouri M, et al. Among authors: croucher dr. Oncogenesis. 2016 Oct 24;5(10):e266. doi: 10.1038/oncsis.2016.66. Oncogenesis. 2016. PMID: 27775700 Free PMC article.
Dissecting Multi-protein Signaling Complexes by Bimolecular Complementation Affinity Purification (BiCAP).
Hastings JF, Han JZR, Shearer RF, Kennedy SP, Iconomou M, Saunders DN, Croucher DR. Hastings JF, et al. Among authors: croucher dr. J Vis Exp. 2018 Jun 15;(136):57109. doi: 10.3791/57109. J Vis Exp. 2018. PMID: 29985350 Free PMC article.
Applications of personalised signalling network models in precision oncology.
Hastings JF, O'Donnell YEI, Fey D, Croucher DR. Hastings JF, et al. Among authors: croucher dr. Pharmacol Ther. 2020 Aug;212:107555. doi: 10.1016/j.pharmthera.2020.107555. Epub 2020 Apr 19. Pharmacol Ther. 2020. PMID: 32320730 Review.
The extracellular matrix as a key regulator of intracellular signalling networks.
Hastings JF, Skhinas JN, Fey D, Croucher DR, Cox TR. Hastings JF, et al. Among authors: croucher dr. Br J Pharmacol. 2019 Jan;176(1):82-92. doi: 10.1111/bph.14195. Epub 2018 Apr 19. Br J Pharmacol. 2019. PMID: 29510460 Free PMC article. Review.
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