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Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability.
Crowley RS, Riley AP, Sherwood AM, Groer CE, Shivaperumal N, Biscaia M, Paton K, Schneider S, Provasi D, Kivell BM, Filizola M, Prisinzano TE. Crowley RS, et al. J Med Chem. 2016 Dec 22;59(24):11027-11038. doi: 10.1021/acs.jmedchem.6b01235. Epub 2016 Dec 13. J Med Chem. 2016. PMID: 27958743 Free PMC article.
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Design, Synthesis, and Evaluation of Analogues with Improved Potency and G-protein Activation Bias at the μ-Opioid Receptor.
Crowley RS, Riley AP, Alder AF, Anderson RJ 3rd, Luo D, Kaska S, Maynez P, Kivell BM, Prisinzano TE. Crowley RS, et al. ACS Chem Neurosci. 2020 Jun 17;11(12):1781-1790. doi: 10.1021/acschemneuro.0c00191. Epub 2020 May 26. ACS Chem Neurosci. 2020. PMID: 32383854 Free PMC article.
Modular Approach to pseudo-Neoclerodanes as Designer κ-Opioid Ligands.
Sherwood AM, Williamson SE, Crowley RS, Abbott LM, Day VW, Prisinzano TE. Sherwood AM, et al. Among authors: crowley rs. Org Lett. 2017 Oct 6;19(19):5414-5417. doi: 10.1021/acs.orglett.7b02684. Epub 2017 Sep 14. Org Lett. 2017. PMID: 28910112 Free PMC article.
70 results