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Structures of filaments from Pick's disease reveal a novel tau protein fold.
Falcon B, Zhang W, Murzin AG, Murshudov G, Garringer HJ, Vidal R, Crowther RA, Ghetti B, Scheres SHW, Goedert M. Falcon B, et al. Among authors: crowther ra. Nature. 2018 Sep;561(7721):137-140. doi: 10.1038/s41586-018-0454-y. Epub 2018 Aug 29. Nature. 2018. PMID: 30158706 Free PMC article.
Propagation of Tau Aggregates and Neurodegeneration.
Goedert M, Eisenberg DS, Crowther RA. Goedert M, et al. Among authors: crowther ra. Annu Rev Neurosci. 2017 Jul 25;40:189-210. doi: 10.1146/annurev-neuro-072116-031153. Annu Rev Neurosci. 2017. PMID: 28772101 Review.
Cryo-EM structures of tau filaments from Alzheimer's disease.
Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ, Crowther RA, Ghetti B, Goedert M, Scheres SHW. Fitzpatrick AWP, et al. Among authors: crowther ra. Nature. 2017 Jul 13;547(7662):185-190. doi: 10.1038/nature23002. Epub 2017 Jul 5. Nature. 2017. PMID: 28678775 Free PMC article.
Preface.
Crowther RA. Crowther RA. Methods Enzymol. 2016;579:xiii-xx. doi: 10.1016/S0076-6879(16)30228-2. Methods Enzymol. 2016. PMID: 27572736 No abstract available.
A Brief History of Tau.
Goedert M, Spillantini MG, Crowther RA. Goedert M, et al. Among authors: crowther ra. Clin Chem. 2015 Nov;61(11):1417-8. doi: 10.1373/clinchem.2015.245142. Epub 2015 Sep 1. Clin Chem. 2015. PMID: 26330509 No abstract available.
Tau pathology is present in vivo and develops in vitro in sensory neurons from human P301S tau transgenic mice: a system for screening drugs against tauopathies.
Mellone M, Kestoras D, Andrews MR, Dassie E, Crowther RA, Stokin GB, Tinsley J, Horne G, Goedert M, Tolkovsky AM, Spillantini MG. Mellone M, et al. Among authors: crowther ra. J Neurosci. 2013 Nov 13;33(46):18175-89. doi: 10.1523/JNEUROSCI.4933-12.2013. J Neurosci. 2013. PMID: 24227726 Free PMC article.
Brain homogenates from human tauopathies induce tau inclusions in mouse brain.
Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J, Probst A, Winkler DT, Reichwald J, Staufenbiel M, Ghetti B, Goedert M, Tolnay M. Clavaguera F, et al. Among authors: crowther ra. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9535-40. doi: 10.1073/pnas.1301175110. Epub 2013 May 20. Proc Natl Acad Sci U S A. 2013. PMID: 23690619 Free PMC article.
142 results