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Hepatic FGF21 is not required for fasting metabolism but guides protein appetite post energy depletion.
Bruse J, Marbach C, Polizzi A, Landre T, Salvi J, Alquier-Bacquie V, Chen SP, Huillet M, Rives C, Martin CMP, Perrier P, Benhamed F, Régnier M, Weger S, Naylies C, Lippi Y, Sommer C, Albin M, Lasserre F, Levade T, Schupp M, Gamet-Payrastre L, Kautz L, Loiseau N, Wahli W, Ellero-Simatos S, Cruciani-Guglielmacci C, Montagner A, Benani A, Postic C, Guillou H, Fougerat A. Bruse J, et al. Among authors: cruciani guglielmacci c. EMBO Rep. 2026 Apr 27. doi: 10.1038/s44319-026-00790-9. Online ahead of print. EMBO Rep. 2026. PMID: 42045447 Free article.
Unraveling the brain expression of bdnf in a mouse model of anorexia nervosa.
Cao J, Lebrun N, Chen SP, Tezenas du Montcel C, Gorwood P, Cruciani-Guglielmacci C, Tolle V, Ramoz N, Viltart O. Cao J, et al. Among authors: cruciani guglielmacci c. Transl Psychiatry. 2025 Oct 17;15(1):417. doi: 10.1038/s41398-025-03618-7. Transl Psychiatry. 2025. PMID: 41107234 Free PMC article.
The GLP-1 analog, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice.
Mermet M, Denom J, Mieczkowska A, Wery M, Biggs E, Gribble FM, Reimann F, Magnan C, Cruciani-Guglielmacci C, Mabilleau G. Mermet M, et al. Among authors: cruciani guglielmacci c. Am J Physiol Endocrinol Metab. 2025 Oct 1;329(4):E522-E536. doi: 10.1152/ajpendo.00086.2025. Epub 2025 Aug 11. Am J Physiol Endocrinol Metab. 2025. PMID: 40789661 Free PMC article.
Serine palmitoyltransferase-mediated de novo sphingolipid biosynthesis is required for normal insulin production and glucose tolerance.
Amouyal C, Chen SP, Denom J, Raho I, Kassis N, Diedisheim M, Mifsud F, Lallement J, Georgiadou E, Ibberson M, Croyal M, Jiang XC, Cruciani-Guglielmacci C, Le Stunff H, Rutter GA, Magnan C. Amouyal C, et al. Among authors: cruciani guglielmacci c. bioRxiv [Preprint]. 2025 May 17:2025.05.14.653935. doi: 10.1101/2025.05.14.653935. bioRxiv. 2025. PMID: 40463068 Free PMC article. Preprint.
ABCG1 orchestrates adipose tissue macrophage plasticity and insulin resistance in obesity by rewiring saturated fatty acid pools.
Dahik VD, Kc P, Materne C, Reydellet C, Lhomme M, Cruciani-Guglielmacci C, Denom J, Bun E, Ponnaiah M, Deknuydt F, Frisdal E, Hardy LM, Durand H, Guillas I, Lesnik P, Gudelj I, Lauc G, Guérin M, Kontush A, Soprani A, Magnan C, Diedisheim M, Bluteau O, Venteclef N, Le Goff W. Dahik VD, et al. Among authors: cruciani guglielmacci c. Sci Transl Med. 2024 Dec 11;16(777):eadi6682. doi: 10.1126/scitranslmed.adi6682. Epub 2024 Dec 11. Sci Transl Med. 2024. PMID: 39661702
A multiorgan map of metabolic, signaling, and inflammatory pathways that coordinately control fasting glycemia in mice.
Mehl F, Sánchez-Archidona AR, Meitil I, Gerl M, Cruciani-Guglielmacci C, Wigger L, Le Stunff H, Meneyrol K, Lallement J, Denom J, Klose C, Simons K, Pagni M, Magnan C, Ibberson M, Thorens B. Mehl F, et al. Among authors: cruciani guglielmacci c. iScience. 2024 Oct 11;27(11):111134. doi: 10.1016/j.isci.2024.111134. eCollection 2024 Nov 15. iScience. 2024. PMID: 39507247 Free PMC article.
Preterm birth: A neuroinflammatory origin for metabolic diseases?
Diao S, Chen C, Benani A, Magnan C, Van Steenwinckel J, Gressens P, Cruciani-Guglielmacci C, Jacquens A, Bokobza C. Diao S, et al. Among authors: cruciani guglielmacci c. Brain Behav Immun Health. 2024 Mar 7;37:100745. doi: 10.1016/j.bbih.2024.100745. eCollection 2024 May. Brain Behav Immun Health. 2024. PMID: 38511150 Free PMC article. Review.
67 results