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p63 Is essential for the proliferative potential of stem cells in stratified epithelia.
Senoo M, Pinto F, Crum CP, McKeon F. Senoo M, et al. Among authors: crum cp. Cell. 2007 May 4;129(3):523-36. doi: 10.1016/j.cell.2007.02.045. Cell. 2007. PMID: 17482546
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development.
Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT, Tabin C, Sharpe A, Caput D, Crum C, McKeon F. Yang A, et al. Among authors: crum c. Nature. 1999 Apr 22;398(6729):714-8. doi: 10.1038/19539. Nature. 1999. PMID: 10227294
Expression of the p53 homologue p63 in early cervical neoplasia.
Quade BJ, Yang A, Wang Y, Sun D, Park J, Sheets EE, Cviko A, Federschneider JM, Peters R, McKeon FD, Crum CP. Quade BJ, et al. Among authors: crum cp. Gynecol Oncol. 2001 Jan;80(1):24-9. doi: 10.1006/gyno.2000.5953. Gynecol Oncol. 2001. PMID: 11136565
Identification of a basal/reserve cell immunophenotype in benign and neoplastic endometrium: a study with the p53 homologue p63.
O'Connell JT, Mutter GL, Cviko A, Nucci M, Quade BJ, Kozakewich HP, Neffen E, Sun D, Yang A, McKeon FD, Crum CP. O'Connell JT, et al. Among authors: crum cp. Gynecol Oncol. 2001 Jan;80(1):30-6. doi: 10.1006/gyno.2000.6026. Gynecol Oncol. 2001. PMID: 11136566
Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation.
Talora C, Sgroi DC, Crum CP, Dotto GP. Talora C, et al. Among authors: crum cp. Genes Dev. 2002 Sep 1;16(17):2252-63. doi: 10.1101/gad.988902. Genes Dev. 2002. PMID: 12208848 Free PMC article.
p63 Coordinates anogenital modeling and epithelial cell differentiation in the developing female urogenital tract.
Ince TA, Cviko AP, Quade BJ, Yang A, McKeon FD, Mutter GL, Crum CP. Ince TA, et al. Among authors: crum cp. Am J Pathol. 2002 Oct;161(4):1111-7. doi: 10.1016/S0002-9440(10)64387-8. Am J Pathol. 2002. PMID: 12368184 Free PMC article.
Loss of p63 expression is associated with tumor progression in bladder cancer.
Urist MJ, Di Como CJ, Lu ML, Charytonowicz E, Verbel D, Crum CP, Ince TA, McKeon FD, Cordon-Cardo C. Urist MJ, et al. Among authors: crum cp. Am J Pathol. 2002 Oct;161(4):1199-206. doi: 10.1016/S0002-9440(10)64396-9. Am J Pathol. 2002. PMID: 12368193 Free PMC article.
Co-expression of p16(INK4A) and laminin 5 gamma2 by microinvasive and superficial squamous cell carcinomas in vivo and by migrating wound and senescent keratinocytes in culture.
Natarajan E, Saeb M, Crum CP, Woo SB, McKee PH, Rheinwald JG. Natarajan E, et al. Among authors: crum cp. Am J Pathol. 2003 Aug;163(2):477-91. doi: 10.1016/s0002-9440(10)63677-2. Am J Pathol. 2003. PMID: 12875969 Free PMC article.
Microglandular hyperplasia: a model for the de novo emergence and evolution of endocervical reserve cells.
Witkiewicz AK, Hecht JL, Cviko A, McKeon FD, Ince TA, Crum CP. Witkiewicz AK, et al. Among authors: crum cp. Hum Pathol. 2005 Feb;36(2):154-61. doi: 10.1016/j.humpath.2004.10.017. Hum Pathol. 2005. PMID: 15754292
p63 protects the female germ line during meiotic arrest.
Suh EK, Yang A, Kettenbach A, Bamberger C, Michaelis AH, Zhu Z, Elvin JA, Bronson RT, Crum CP, McKeon F. Suh EK, et al. Among authors: crum cp. Nature. 2006 Nov 30;444(7119):624-8. doi: 10.1038/nature05337. Epub 2006 Nov 22. Nature. 2006. PMID: 17122775
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