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Page 1
Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.
Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME. Crunkhorn S, et al. J Biol Chem. 2007 May 25;282(21):15439-50. doi: 10.1074/jbc.M611214200. Epub 2007 Apr 6. J Biol Chem. 2007. PMID: 17416903 Free article.
Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes.
Espinoza DO, Boros LG, Crunkhorn S, Gami H, Patti ME. Espinoza DO, et al. Among authors: crunkhorn s. FASEB J. 2010 Apr;24(4):1003-14. doi: 10.1096/fj.09-133728. Epub 2009 Nov 11. FASEB J. 2010. PMID: 19906680 Free PMC article.
These results indicate that PGC-1 can promote both lipid oxidation and synthesis, with net balance determined by the nutrient/hormonal environment.-Espinoza, D. O., Boros, L. G., Crunkhorn, S., Gami, H., Patti, M.-E. Dual Modulation of both lipid oxidation and synth …
These results indicate that PGC-1 can promote both lipid oxidation and synthesis, with net balance determined by the nutrient/hormonal envir …
Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis.
Pihlajamäki J, Lerin C, Itkonen P, Boes T, Floss T, Schroeder J, Dearie F, Crunkhorn S, Burak F, Jimenez-Chillaron JC, Kuulasmaa T, Miettinen P, Park PJ, Nasser I, Zhao Z, Zhang Z, Xu Y, Wurst W, Ren H, Morris AJ, Stamm S, Goldfine AB, Laakso M, Patti ME. Pihlajamäki J, et al. Among authors: crunkhorn s. Cell Metab. 2011 Aug 3;14(2):208-18. doi: 10.1016/j.cmet.2011.06.007. Cell Metab. 2011. PMID: 21803291 Free PMC article.
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1.
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, Mandarino LJ. Patti ME, et al. Among authors: crunkhorn s. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8466-71. doi: 10.1073/pnas.1032913100. Epub 2003 Jun 27. Proc Natl Acad Sci U S A. 2003. PMID: 12832613 Free PMC article.
Response to Brosch et al.
Pihlajamäki J, Lerin C, Kaminska D, Venesmaa S, Itkonen P, Boes T, Floss T, Schroeder J, Dearie F, Crunkhorn S, Burak F, Jimenez-Chillaron JC, Kuulasmaa T, Miettinen P, Park PJ, Nasser I, Zhao Z, Zhang Z, Xu Y, Wurst W, Ren H, Morris AJ, Stamm S, Goldfine AB, Laakso M, Patti ME. Pihlajamäki J, et al. Among authors: crunkhorn s. Cell Metab. 2012 Mar 7;15(3):267-269. doi: 10.1016/j.cmet.2012.02.005. Cell Metab. 2012. PMID: 25960695 Free PMC article.
Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle.
Kuhl JE, Ruderman NB, Musi N, Goodyear LJ, Patti ME, Crunkhorn S, Dronamraju D, Thorell A, Nygren J, Ljungkvist O, Degerblad M, Stahle A, Brismar TB, Andersen KL, Saha AK, Efendic S, Bavenholm PN. Kuhl JE, et al. Among authors: crunkhorn s. Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1296-303. doi: 10.1152/ajpendo.00341.2005. Epub 2006 Jan 24. Am J Physiol Endocrinol Metab. 2006. PMID: 16434556 Free article. Clinical Trial.
Targeted design of protein binders.
Crunkhorn S. Crunkhorn S. Nat Rev Drug Discov. 2022 Jun;21(6):416. doi: 10.1038/d41573-022-00084-4. Nat Rev Drug Discov. 2022. PMID: 35523894 No abstract available.
549 results