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High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses.
De BP, Heguy A, Hackett NR, Ferris B, Leopold PL, Lee J, Pierre L, Gao G, Wilson JM, Crystal RG. De BP, et al. Among authors: crystal rg. Mol Ther. 2006 Jan;13(1):67-76. doi: 10.1016/j.ymthe.2005.09.003. Epub 2005 Nov 2. Mol Ther. 2006. PMID: 16260185 Free article.
Safety of direct administration of AAV2(CU)hCLN2, a candidate treatment for the central nervous system manifestations of late infantile neuronal ceroid lipofuscinosis, to the brain of rats and nonhuman primates.
Hackett NR, Redmond DE, Sondhi D, Giannaris EL, Vassallo E, Stratton J, Qiu J, Kaminsky SM, Lesser ML, Fisch GS, Rouselle SD, Crystal RG. Hackett NR, et al. Among authors: crystal rg. Hum Gene Ther. 2005 Dec;16(12):1484-503. doi: 10.1089/hum.2005.16.1484. Hum Gene Ther. 2005. PMID: 16390279
907 results