mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response.
Fonseca D, Baquero J, Murphy MR, Aruggoda G, Varriano S, Sapienza C, Mashadova O, Rahman S, Kleiman FE.
Fonseca D, et al.
Mol Cell Biol. 2018 Jan 29;38(4):e00364-17. doi: 10.1128/MCB.00364-17. Print 2018 Feb 15.
Mol Cell Biol. 2018.
PMID: 29180510
Free PMC article.
CstF-50 and p97 formed complexes with BRCA1/BARD1, Ub, and some BRCA1/BARD1 substrates, such as RNA polymerase (RNAP) II and histones. Furthermore, CstF-50 and p97 had an additive effect on the activation of the ubiquitination of these BRCA1/BARD1 subs …
CstF-50 and p97 formed complexes with BRCA1/BARD1, Ub, and some BRCA1/BARD1 substrates, such as RNA polymerase (RNAP) II and h …