Cua DJ - Search Results

1

Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

Chen Y, Haines CJ, Gutcher I, Hochweller K, Blumenschein WM, McClanahan T, Hämmerling G, Li MO, Cua DJ, McGeachy MJ. Chen Y, et al. Among authors: cua dj. Immunity. 2011 Mar 25;34(3):409-21. doi: 10.1016/j.immuni.2011.02.011. Immunity. 2011. PMID: 21435588 Free article.

2

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, de Waal-Malefyt R, Coffman RL, Hawrylowicz CM, O'Garra A. Barrat FJ, et al. Among authors: cua dj. J Exp Med. 2002 Mar 4;195(5):603-16. doi: 10.1084/jem.20011629. J Exp Med. 2002. PMID: 11877483 Free PMC article.

3

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.

Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD. Cua DJ, et al. Nature. 2003 Feb 13;421(6924):744-8. doi: 10.1038/nature01355. Nature. 2003. PMID: 12610626

4

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation.

Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, Sedgwick JD, Cua DJ. Murphy CA, et al. Among authors: cua dj. J Exp Med. 2003 Dec 15;198(12):1951-7. doi: 10.1084/jem.20030896. Epub 2003 Dec 8. J Exp Med. 2003. PMID: 14662908 Free PMC article.

5

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation.

Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T, Kastelein RA, Cua DJ. Langrish CL, et al. Among authors: cua dj. J Exp Med. 2005 Jan 17;201(2):233-40. doi: 10.1084/jem.20041257. J Exp Med. 2005. PMID: 15657292 Free PMC article.

6

Understanding the IL-23-IL-17 immune pathway.

McKenzie BS, Kastelein RA, Cua DJ. McKenzie BS, et al. Among authors: cua dj. Trends Immunol. 2006 Jan;27(1):17-23. doi: 10.1016/j.it.2005.10.003. Epub 2005 Nov 14. Trends Immunol. 2006. PMID: 16290228

7

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract.

Owyang AM, Zaph C, Wilson EH, Guild KJ, McClanahan T, Miller HR, Cua DJ, Goldschmidt M, Hunter CA, Kastelein RA, Artis D. Owyang AM, et al. Among authors: cua dj. J Exp Med. 2006 Apr 17;203(4):843-9. doi: 10.1084/jem.20051496. Epub 2006 Apr 10. J Exp Med. 2006. PMID: 16606667 Free PMC article.

8

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6.

Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, Kleinschek MA, Owyang A, Mattson J, Blumenschein W, Murphy E, Sathe M, Cua DJ, Kastelein RA, Rennick D. Yen D, et al. Among authors: cua dj. J Clin Invest. 2006 May;116(5):1310-6. doi: 10.1172/JCI21404. J Clin Invest. 2006. PMID: 16670770 Free PMC article.

9

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis.

Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ. Chen Y, et al. Among authors: cua dj. J Clin Invest. 2006 May;116(5):1317-26. doi: 10.1172/JCI25308. J Clin Invest. 2006. PMID: 16670771 Free PMC article.

10

IL-25 regulates Th17 function in autoimmune inflammation.

Kleinschek MA, Owyang AM, Joyce-Shaikh B, Langrish CL, Chen Y, Gorman DM, Blumenschein WM, McClanahan T, Brombacher F, Hurst SD, Kastelein RA, Cua DJ. Kleinschek MA, et al. Among authors: cua dj. J Exp Med. 2007 Jan 22;204(1):161-70. doi: 10.1084/jem.20061738. Epub 2007 Jan 2. J Exp Med. 2007. PMID: 17200411 Free PMC article.

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