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Relative importance of intestinal and hepatic glucuronidation-impact on the prediction of drug clearance.

Cubitt HE, Houston JB, Galetin A. Cubitt HE, et al. Pharm Res. 2009 May;26(5):1073-83. doi: 10.1007/s11095-008-9823-9. Epub 2009 Jan 31. Pharm Res. 2009. PMID: 19184618

Prediction of human drug clearance by multiple metabolic pathways: integration of hepatic and intestinal microsomal and cytosolic data.

Cubitt HE, Houston JB, Galetin A. Cubitt HE, et al. Drug Metab Dispos. 2011 May;39(5):864-73. doi: 10.1124/dmd.110.036566. Epub 2011 Feb 8. Drug Metab Dispos. 2011. PMID: 21303923

Sources of interindividual variability in IVIVE of clearance: an investigation into the prediction of benzodiazepine clearance using a mechanistic population-based pharmacokinetic model.

Cubitt HE, Yeo KR, Howgate EM, Rostami-Hodjegan A, Barter ZE. Cubitt HE, et al. Xenobiotica. 2011 Aug;41(8):623-38. doi: 10.3109/00498254.2011.560294. Epub 2011 Mar 24. Xenobiotica. 2011. PMID: 21434772

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