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The CYP2C19*17 allele is associated with better platelet response to clopidogrel in patients admitted for non-ST acute coronary syndrome.
Frére C, Cuisset T, Gaborit B, Alessi MC, Hulot JS. Frére C, et al. J Thromb Haemost. 2009 Aug;7(8):1409-11. doi: 10.1111/j.1538-7836.2009.03500.x. Epub 2009 May 30. J Thromb Haemost. 2009. PMID: 19496924 No abstract available.
High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome.
Cuisset T, Frere C, Quilici J, Barbou F, Morange PE, Hovasse T, Bonnet JL, Alessi MC. Cuisset T, et al. J Thromb Haemost. 2006 Mar;4(3):542-9. doi: 10.1111/j.1538-7836.2005.01751.x. Epub 2005 Dec 22. J Thromb Haemost. 2006. PMID: 16371119 Clinical Trial.
Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting.
Cuisset T, Frere C, Quilici J, Morange PE, Nait-Saidi L, Carvajal J, Lehmann A, Lambert M, Bonnet JL, Alessi MC. Cuisset T, et al. J Am Coll Cardiol. 2006 Oct 3;48(7):1339-45. doi: 10.1016/j.jacc.2006.06.049. Epub 2006 Sep 12. J Am Coll Cardiol. 2006. PMID: 17010792 Clinical Trial.
[Beneficial effect of a loading dose of 600 mg of clopidogrel on platelet parameters in patients admitted for acute coronary syndrome].
Cuisset T, Frère C, Quilici J, Morange PE, Saidi LN, Carvajal J, Lambert M, Mouret JP, Alessi MC, Bonnet JL. Cuisset T, et al. Arch Mal Coeur Vaiss. 2006 Oct;99(10):889-93. Arch Mal Coeur Vaiss. 2006. PMID: 17100139 French.
Lack of association between the 807 C/T polymorphism of glycoprotein Ia gene and post-treatment platelet reactivity after aspirin and clopidogrel in patients with acute coronary syndrome.
Cuisset T, Frere C, Quilici J, Morange PE, Saut N, Romero-Barra M, Camoin L, Lambert M, Juhan-Vague I, Bonnet JL, Alessi MC. Cuisset T, et al. Thromb Haemost. 2007 Feb;97(2):212-7. Thromb Haemost. 2007. PMID: 17264949 Clinical Trial.
The genotype frequencies of the 807 C/T polymorphism of the GpIa gene were similar in responders and non-responders defined by persistent HPPR (p=0.104). In conclusion, our study did not show any influence of 807 C/T polymorphism of GpIa gene on post-treatment plate …
The genotype frequencies of the 807 C/T polymorphism of the GpIa gene were similar in responders and non-responders defined by persis …
High post-treatment platelet reactivity is associated with a high incidence of myonecrosis after stenting for non-ST elevation acute coronary syndromes.
Cuisset T, Frere C, Quilici J, Morange PE, Nait-Saidi L, Mielot C, Bali L, Lambert M, Alessi MC, Bonnet JL. Cuisset T, et al. Thromb Haemost. 2007 Feb;97(2):282-7. Thromb Haemost. 2007. PMID: 17264958
Role of the T744C polymorphism of the P2Y12 gene on platelet response to a 600-mg loading dose of clopidogrel in 597 patients with non-ST-segment elevation acute coronary syndrome.
Cuisset T, Frere C, Quilici J, Morange PE, Saut N, Lambert M, Camoin L, Vague IJ, Bonnet JL, Alessi MC. Cuisset T, et al. Thromb Res. 2007;120(6):893-9. doi: 10.1016/j.thromres.2007.01.012. Epub 2007 Mar 6. Thromb Res. 2007. PMID: 17337040
ADP-induced platelet aggregation and platelet reactivity index VASP are good predictive markers for clinical outcomes in non-ST elevation acute coronary syndrome.
Frere C, Cuisset T, Quilici J, Camoin L, Carvajal J, Morange PE, Lambert M, Juhan-Vague I, Bonnet JL, Alessi MC. Frere C, et al. Thromb Haemost. 2007 Oct;98(4):838-43. Thromb Haemost. 2007. PMID: 17938809
Effect of cytochrome p450 polymorphisms on platelet reactivity after treatment with clopidogrel in acute coronary syndrome.
Frere C, Cuisset T, Morange PE, Quilici J, Camoin-Jau L, Saut N, Faille D, Lambert M, Juhan-Vague I, Bonnet JL, Alessi MC. Frere C, et al. Am J Cardiol. 2008 Apr 15;101(8):1088-93. doi: 10.1016/j.amjcard.2007.11.065. Epub 2008 Feb 6. Am J Cardiol. 2008. PMID: 18394438
Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response.
Cuisset T, Frere C, Quilici J, Morange PE, Camoin L, Bali L, Lambert M, Juhan-Vague I, Alessi MC, Bonnet JL. Cuisset T, et al. Thromb Res. 2009 Feb;123(4):597-603. doi: 10.1016/j.thromres.2008.04.003. Epub 2008 May 21. Thromb Res. 2009. PMID: 18499233
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