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Discovery and characterization of novel tryptophan hydroxylase inhibitors that selectively inhibit serotonin synthesis in the gastrointestinal tract.
Liu Q, Yang Q, Sun W, Vogel P, Heydorn W, Yu XQ, Hu Z, Yu W, Jonas B, Pineda R, Calderon-Gay V, Germann M, O'Neill E, Brommage R, Cullinan E, Platt K, Wilson A, Powell D, Sands A, Zambrowicz B, Shi ZC. Liu Q, et al. J Pharmacol Exp Ther. 2008 Apr;325(1):47-55. doi: 10.1124/jpet.107.132670. Epub 2008 Jan 11. J Pharmacol Exp Ther. 2008. PMID: 18192499
Reproduction in mice lacking a functional type 1 IL-1 receptor.
Abbondanzo SJ, Cullinan EB, McIntyre K, Labow MA, Stewart CL. Abbondanzo SJ, et al. Among authors: cullinan eb. Endocrinology. 1996 Aug;137(8):3598-601. doi: 10.1210/endo.137.8.8754793. Endocrinology. 1996. PMID: 8754793
15 results