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Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model.
Santa-Maria AR, Walter FR, Figueiredo R, Kincses A, Vigh JP, Heymans M, Culot M, Winter P, Gosselet F, Dér A, Deli MA. Santa-Maria AR, et al. Among authors: culot m. J Cereb Blood Flow Metab. 2021 Sep;41(9):2201-2215. doi: 10.1177/0271678X21992638. Epub 2021 Feb 9. J Cereb Blood Flow Metab. 2021. PMID: 33563079 Free PMC article.
Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability.
De Bock M, Culot M, Wang N, Bol M, Decrock E, De Vuyst E, da Costa A, Dauwe I, Vinken M, Simon AM, Rogiers V, De Ley G, Evans WH, Bultynck G, Dupont G, Cecchelli R, Leybaert L. De Bock M, et al. Among authors: culot m. J Cereb Blood Flow Metab. 2011 Sep;31(9):1942-57. doi: 10.1038/jcbfm.2011.86. Epub 2011 Jun 8. J Cereb Blood Flow Metab. 2011. PMID: 21654699 Free PMC article.
Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models.
Schultz L, Zurich MG, Culot M, da Costa A, Landry C, Bellwon P, Kristl T, Hörmann K, Ruzek S, Aiche S, Reinert K, Bielow C, Gosselet F, Cecchelli R, Huber CG, Schroeder OH, Gramowski-Voss A, Weiss DG, Bal-Price A. Schultz L, et al. Among authors: culot m. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):138-65. doi: 10.1016/j.tiv.2015.05.016. Epub 2015 May 27. Toxicol In Vitro. 2015. PMID: 26026931 Free article.
Corrigendum to "Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration" [Eur. J. Pharm. Biopharm. 127 (2018) 453-461].
Heymans M, Sevin E, Gosselet F, Lundquist S, Culot M. Heymans M, et al. Among authors: culot m. Eur J Pharm Biopharm. 2018 Dec;133:200-202. doi: 10.1016/j.ejpb.2018.10.012. Epub 2018 Oct 27. Eur J Pharm Biopharm. 2018. PMID: 30458954 No abstract available.
57 results