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Cuminaldehyde potentiates the antimicrobial actions of ciprofloxacin against Staphylococcus aureus and Escherichia coli.
Monteiro-Neto V, de Souza CD, Gonzaga LF, da Silveira BC, Sousa NCF, Pontes JP, Santos DM, Martins WC, Pessoa JFV, Carvalho Júnior AR, Almeida VSS, de Oliveira NMT, de Araújo TS, Maria-Ferreira D, Mendes SJF, Ferro TAF, Fernandes ES. Monteiro-Neto V, et al. PLoS One. 2020 May 14;15(5):e0232987. doi: 10.1371/journal.pone.0232987. eCollection 2020. PLoS One. 2020. PMID: 32407399 Free PMC article.
In silico analysis indicated that cuminaldehyde may act as an antimicrobial and as a membrane permeability enhancer. ...Cuminaldehyde presented antimicrobial and anti-biofilm effects against S. aureus and E. coli.. ...
In silico analysis indicated that cuminaldehyde may act as an antimicrobial and as a membrane permeability enhancer. ...Cuminaldeh
Novel cuminaldehyde self-emulsified nanoemulsion for enhanced antihepatotoxicity in carbon tetrachloride-treated mice.
Adu-Frimpong M, Qiuyu W, Firempong CK, Mukhtar YM, Yang Q, Omari-Siaw E, Lijun Z, Xu X, Yu J. Adu-Frimpong M, et al. J Pharm Pharmacol. 2019 Aug;71(8):1324-1338. doi: 10.1111/jphp.13112. Epub 2019 Jun 5. J Pharm Pharmacol. 2019. PMID: 31168820
OBJECTIVES: Cuminaldehyde self-emulsified nanoemulsion (CuA-SEN) was prepared and optimised to improve its oral bioavailability and antihepatotoxicity. METHODS: Cuminaldehyde self-emulsified nanoemulsion was developed through the self-nanoemulsification method using …
OBJECTIVES: Cuminaldehyde self-emulsified nanoemulsion (CuA-SEN) was prepared and optimised to improve its oral bioavailability and a …
Antinociceptive and antineuropathic effects of cuminaldehyde, the major constituent of Cuminum cyminum seeds: Possible mechanisms of action.
Koohsari S, Sheikholeslami MA, Parvardeh S, Ghafghazi S, Samadi S, Poul YK, Pouriran R, Amiri S. Koohsari S, et al. J Ethnopharmacol. 2020 Jun 12;255:112786. doi: 10.1016/j.jep.2020.112786. Epub 2020 Mar 25. J Ethnopharmacol. 2020. PMID: 32222574
ETHNOPHARMACOLOGICAL RELEVANCE: In Iranian traditional medicine, Cuminum cyminum is a unique medicinal herb for pain relief. Cuminaldehyde has been distinguished as the major constituent of C. cyminum seeds; even though, the analgesic effect of cuminaldehyde has not …
ETHNOPHARMACOLOGICAL RELEVANCE: In Iranian traditional medicine, Cuminum cyminum is a unique medicinal herb for pain relief. Cuminaldehyd
Cuminaldehyde induces oxidative stress-mediated physical damage and death of Haemonchus contortus.
Goel V, Singla LD, Choudhury D. Goel V, et al. Biomed Pharmacother. 2020 Oct;130:110411. doi: 10.1016/j.biopha.2020.110411. Epub 2020 Jul 16. Biomed Pharmacother. 2020. PMID: 32682984 Free article.
Cuminaldehyde (CA), a monoterpenoid, preset in many plant sources including cumin, induces reactive oxygen-related damage and death in Haemonchus contortus, a parasitic worm with an LD50, values of 127.3 7.5, 184.5 12.1 and 104.1 7.9 mug/mL for an adult female, adult male
Cuminaldehyde (CA), a monoterpenoid, preset in many plant sources including cumin, induces reactive oxygen-related damage and death i
Cuminaldehyde as a lipoxygenase inhibitor: in vitro and in silico validation.
Tomy MJ, Dileep KV, Prasanth S, Preethidan DS, Sabu A, Sadasivan C, Haridas M. Tomy MJ, et al. Appl Biochem Biotechnol. 2014 Sep;174(1):388-97. doi: 10.1007/s12010-014-1066-0. Epub 2014 Jul 31. Appl Biochem Biotechnol. 2014. PMID: 25080377
Activity-guided screening of the C. cyminum crude extracts helped the identification and isolation of cuminaldehyde as a 15-LOX inhibitor. The enzyme kinetics analysis suggested cuminaldehyde to be a competitive inhibitor and the IC 50 value derived from LB plots is …
Activity-guided screening of the C. cyminum crude extracts helped the identification and isolation of cuminaldehyde as a 15-LOX inhib …
Spice use in food: Properties and benefits.
Jessica Elizabeth T, Gassara F, Kouassi AP, Brar SK, Belkacemi K. Jessica Elizabeth T, et al. Crit Rev Food Sci Nutr. 2017 Apr 13;57(6):1078-1088. doi: 10.1080/10408398.2013.858235. Crit Rev Food Sci Nutr. 2017. PMID: 26560460 Review.
The uses of spices have been known since long time, and the interest in the potential of spices is remarkable due to the chemical compounds contained in spices, such as phenylpropanoids, terpenes, flavonoids, and anthocyanins. Spices, such as cumin (cuminaldehyde), clove ( …
The uses of spices have been known since long time, and the interest in the potential of spices is remarkable due to the chemical compounds …
Aromatic aldehyde compound cuminaldehyde protects nonalcoholic fatty liver disease in rats feeding high fat diet.
Haque MR, Ansari SH. Haque MR, et al. Hum Exp Toxicol. 2019 Jul;38(7):823-832. doi: 10.1177/0960327119842248. Epub 2019 Apr 12. Hum Exp Toxicol. 2019. PMID: 30974975
Our findings suggest that cuminaldehyde could improve HFD-induced NAFLD via abolishment of hepatic oxidative damage and hyperlipidemia. Cuminaldehyde might be considered as a potential aromatic compound in the treatment of NAFLD and obesity through the modulation of …
Our findings suggest that cuminaldehyde could improve HFD-induced NAFLD via abolishment of hepatic oxidative damage and hyperlipidemi …
Ultrasound processed cuminaldehyde/2-hydroxypropyl-beta-cyclodextrin inclusion complex: Preparation, characterization and antibacterial activity.
Cui H, Siva S, Lin L. Cui H, et al. Ultrason Sonochem. 2019 Sep;56:84-93. doi: 10.1016/j.ultsonch.2019.04.001. Epub 2019 Apr 1. Ultrason Sonochem. 2019. PMID: 31101292 Free article.
Ultrasound is an energy saving, simple, high efficiency and eco-friend physical technology. In this study, the inclusion complex of cuminaldehyde (CUM), a major constituent of cumin essential oil, with 2-hydroxypropyl-beta-cyclodextrin (HPbetaCD) was synthesised with the a …
Ultrasound is an energy saving, simple, high efficiency and eco-friend physical technology. In this study, the inclusion complex of cumin
Cuminaldehyde as the Major Component of Cuminum cyminum, a Natural Aldehyde with Inhibitory Effect on Alpha-Synuclein Fibrillation and Cytotoxicity.
Morshedi D, Aliakbari F, Tayaranian-Marvian A, Fassihi A, Pan-Montojo F, Pérez-Sánchez H. Morshedi D, et al. J Food Sci. 2015 Oct;80(10):H2336-45. doi: 10.1111/1750-3841.13016. Epub 2015 Sep 9. J Food Sci. 2015. PMID: 26351865
Analysis of different fractions from the total extract identified cuminaldehyde as the active compound involved in the antifibrillation activity. ...In addition, cytotoxicity assays on PC12 cells showed that cuminaldehyde is a nontoxic compound, treatment with cu
Analysis of different fractions from the total extract identified cuminaldehyde as the active compound involved in the antifibrillati …
Cuminaldehyde from Cinnamomum verum Induces Cell Death through Targeting Topoisomerase 1 and 2 in Human Colorectal Adenocarcinoma COLO 205 Cells.
Tsai KD, Liu YH, Chen TW, Yang SM, Wong HY, Cherng J, Chou KS, Cherng JM. Tsai KD, et al. Nutrients. 2016 May 24;8(6):318. doi: 10.3390/nu8060318. Nutrients. 2016. PMID: 27231935 Free PMC article.
Additional study shows that the anticancer activity of cuminaldehyde was observed in the model of nude mice. Our results suggest that the anticancer activity of cuminaldehyde in vitro involved the suppression of cell proliferative markers, topoisomerase I as well as …
Additional study shows that the anticancer activity of cuminaldehyde was observed in the model of nude mice. Our results suggest that …
117 results