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Liver X receptors and cholesterol homoeostasis: spotlight on the adrenal gland.
Cummins CL, Mangelsdorf DJ. Cummins CL, et al. Biochem Soc Trans. 2006 Dec;34(Pt 6):1110-3. doi: 10.1042/BST0341110. Biochem Soc Trans. 2006. PMID: 17073762 Review.
Quantification of Oxysterol Nuclear Receptor Ligands by LC/MS/MS.
Magomedova L, Cummins CL. Magomedova L, et al. Among authors: cummins cl. Methods Mol Biol. 2019;1951:1-14. doi: 10.1007/978-1-4939-9130-3_1. Methods Mol Biol. 2019. PMID: 30825140
Beyond the Foam Cell: The Role of LXRs in Preventing Atherogenesis.
Rasheed A, Cummins CL. Rasheed A, et al. Among authors: cummins cl. Int J Mol Sci. 2018 Aug 7;19(8):2307. doi: 10.3390/ijms19082307. Int J Mol Sci. 2018. PMID: 30087224 Free PMC article. Review.
Glucocorticoids regulate the metabolic hormone FGF21 in a feed-forward loop.
Patel R, Bookout AL, Magomedova L, Owen BM, Consiglio GP, Shimizu M, Zhang Y, Mangelsdorf DJ, Kliewer SA, Cummins CL. Patel R, et al. Among authors: cummins cl. Mol Endocrinol. 2015 Feb;29(2):213-23. doi: 10.1210/me.2014-1259. Epub 2014 Dec 11. Mol Endocrinol. 2015. PMID: 25495872 Free PMC article.
Liver X receptor modulates diabetic retinopathy outcome in a mouse model of streptozotocin-induced diabetes.
Hazra S, Rasheed A, Bhatwadekar A, Wang X, Shaw LC, Patel M, Caballero S, Magomedova L, Solis N, Yan Y, Wang W, Thinschmidt JS, Verma A, Li Q, Levi M, Cummins CL, Grant MB. Hazra S, et al. Among authors: cummins cl. Diabetes. 2012 Dec;61(12):3270-9. doi: 10.2337/db11-1596. Epub 2012 Aug 13. Diabetes. 2012. PMID: 22891211 Free PMC article.
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.
Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA. Lee YK, et al. Among authors: cummins cl. Mol Endocrinol. 2008 Jun;22(6):1345-56. doi: 10.1210/me.2007-0565. Epub 2008 Mar 6. Mol Endocrinol. 2008. PMID: 18323469 Free PMC article.
Synthesis and activity of dafachronic acid ligands for the C. elegans DAF-12 nuclear hormone receptor.
Sharma KK, Wang Z, Motola DL, Cummins CL, Mangelsdorf DJ, Auchus RJ. Sharma KK, et al. Among authors: cummins cl. Mol Endocrinol. 2009 May;23(5):640-8. doi: 10.1210/me.2008-0415. Epub 2009 Feb 5. Mol Endocrinol. 2009. PMID: 19196833 Free PMC article.
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.
Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA. Inagaki T, et al. Among authors: cummins cl. Cell Metab. 2005 Oct;2(4):217-25. doi: 10.1016/j.cmet.2005.09.001. Cell Metab. 2005. PMID: 16213224
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans.
Motola DL, Cummins CL, Rottiers V, Sharma KK, Li T, Li Y, Suino-Powell K, Xu HE, Auchus RJ, Antebi A, Mangelsdorf DJ. Motola DL, et al. Among authors: cummins cl. Cell. 2006 Mar 24;124(6):1209-23. doi: 10.1016/j.cell.2006.01.037. Epub 2006 Mar 9. Cell. 2006. PMID: 16529801
AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids.
Schmidt DR, Schmidt S, Holmstrom SR, Makishima M, Yu RT, Cummins CL, Mangelsdorf DJ, Kliewer SA. Schmidt DR, et al. Among authors: cummins cl. J Biol Chem. 2011 Jan 28;286(4):2425-32. doi: 10.1074/jbc.M110.181230. Epub 2010 Nov 16. J Biol Chem. 2011. PMID: 21081494 Free PMC article.
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