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Induction of P-glycoprotein by antiretroviral drugs in human brain microvessel endothelial cells.
Chan GN, Patel R, Cummins CL, Bendayan R. Chan GN, et al. Among authors: cummins cl. Antimicrob Agents Chemother. 2013 Sep;57(9):4481-8. doi: 10.1128/AAC.00486-13. Epub 2013 Jul 8. Antimicrob Agents Chemother. 2013. PMID: 23836171 Free PMC article.
Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2).
Flanagan SD, Cummins CL, Susanto M, Liu X, Takahashi LH, Benet LZ. Flanagan SD, et al. Among authors: cummins cl. Pharmacology. 2002;64(3):126-34. doi: 10.1159/000056161. Pharmacology. 2002. PMID: 11834888
LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice.
Patel R, Patel M, Tsai R, Lin V, Bookout AL, Zhang Y, Magomedova L, Li T, Chan JF, Budd C, Mangelsdorf DJ, Cummins CL. Patel R, et al. Among authors: cummins cl. J Clin Invest. 2011 Jan;121(1):431-41. doi: 10.1172/JCI41681. Epub 2010 Dec 1. J Clin Invest. 2011. PMID: 21123945 Free PMC article.
1Alpha,25-dihydroxyvitamin D3 up-regulates P-glycoprotein via the vitamin D receptor and not farnesoid X receptor in both fxr(-/-) and fxr(+/+) mice and increased renal and brain efflux of digoxin in mice in vivo.
Chow EC, Durk MR, Cummins CL, Pang KS. Chow EC, et al. Among authors: cummins cl. J Pharmacol Exp Ther. 2011 Jun;337(3):846-59. doi: 10.1124/jpet.111.179101. Epub 2011 Mar 18. J Pharmacol Exp Ther. 2011. PMID: 21421739
Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells.
Chan GN, Hoque MT, Cummins CL, Bendayan R. Chan GN, et al. Among authors: cummins cl. J Neurochem. 2011 Jul;118(2):163-75. doi: 10.1111/j.1471-4159.2011.07288.x. Epub 2011 May 25. J Neurochem. 2011. PMID: 21517853
Liver X receptors preserve renal glomerular integrity under normoglycaemia and in diabetes in mice.
Patel M, Wang XX, Magomedova L, John R, Rasheed A, Santamaria H, Wang W, Tsai R, Qiu L, Orellana A, Advani A, Levi M, Cummins CL. Patel M, et al. Among authors: cummins cl. Diabetologia. 2014 Feb;57(2):435-46. doi: 10.1007/s00125-013-3095-6. Epub 2013 Nov 8. Diabetologia. 2014. PMID: 24201575
Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.
Chow EC, Magomedova L, Quach HP, Patel R, Durk MR, Fan J, Maeng HJ, Irondi K, Anakk S, Moore DD, Cummins CL, Pang KS. Chow EC, et al. Among authors: cummins cl. Gastroenterology. 2014 Apr;146(4):1048-59. doi: 10.1053/j.gastro.2013.12.027. Epub 2013 Dec 21. Gastroenterology. 2014. PMID: 24365583
Minireview: new molecular mediators of glucocorticoid receptor activity in metabolic tissues.
Patel R, Williams-Dautovich J, Cummins CL. Patel R, et al. Among authors: cummins cl. Mol Endocrinol. 2014 Jul;28(7):999-1011. doi: 10.1210/me.2014-1062. Epub 2014 Apr 25. Mol Endocrinol. 2014. PMID: 24766141 Free PMC article. Review.
Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis.
Bashiri A, Nesan D, Tavallaee G, Sue-Chue-Lam I, Chien K, Maguire GF, Naples M, Zhang J, Magomedova L, Adeli K, Cummins CL, Ng DS. Bashiri A, et al. Among authors: cummins cl. Biochim Biophys Acta. 2016 Jul;1861(7):594-605. doi: 10.1016/j.bbalip.2016.04.005. Epub 2016 Apr 14. Biochim Biophys Acta. 2016. PMID: 27090939
Diet Polyphenol Curcumin Stimulates Hepatic Fgf21 Production and Restores Its Sensitivity in High-Fat-Diet-Fed Male Mice.
Zeng K, Tian L, Patel R, Shao W, Song Z, Liu L, Manuel J, Ma X, McGilvray I, Cummins CL, Weng J, Jin T. Zeng K, et al. Among authors: cummins cl. Endocrinology. 2017 Feb 1;158(2):277-292. doi: 10.1210/en.2016-1596. Endocrinology. 2017. PMID: 27967217
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