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Tumor vasculature targeting through NGR peptide-based drug delivery systems.
Corti A, Curnis F. Corti A, et al. Among authors: curnis f. Curr Pharm Biotechnol. 2011 Aug;12(8):1128-34. doi: 10.2174/138920111796117373. Curr Pharm Biotechnol. 2011. PMID: 21470145 Review.
Tumor targeting with biotinylated tumor necrosis factor alpha: structure-activity relationships and mechanism of action on avidin pretargeted tumor cells.
Corti A, Gasparri A, Sacchi A, Curnis F, Sangregorio R, Colombo B, Siccardi AG, Magni F. Corti A, et al. Among authors: curnis f. Cancer Res. 1998 Sep 1;58(17):3866-72. Cancer Res. 1998. PMID: 9731496
Tumor pretargeting with avidin improves the therapeutic index of biotinylated tumor necrosis factor alpha in mouse models.
Gasparri A, Moro M, Curnis F, Sacchi A, Pagano S, Veglia F, Casorati G, Siccardi AG, Dellabona P, Corti A. Gasparri A, et al. Among authors: curnis f. Cancer Res. 1999 Jun 15;59(12):2917-23. Cancer Res. 1999. PMID: 10383155
Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13).
Curnis F, Sacchi A, Borgna L, Magni F, Gasparri A, Corti A. Curnis F, et al. Nat Biotechnol. 2000 Nov;18(11):1185-90. doi: 10.1038/81183. Nat Biotechnol. 2000. PMID: 11062439
Roles of tumor necrosis factor p55 and p75 receptors in TNF-alpha-induced vascular permeability.
Ferrero E, Zocchi MR, Magni E, Panzeri MC, Curnis F, Rugarli C, Ferrero ME, Corti A. Ferrero E, et al. Among authors: curnis f. Am J Physiol Cell Physiol. 2001 Oct;281(4):C1173-9. doi: 10.1152/ajpcell.2001.281.4.C1173. Am J Physiol Cell Physiol. 2001. PMID: 11546653
Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells.
Curnis F, Arrigoni G, Sacchi A, Fischetti L, Arap W, Pasqualini R, Corti A. Curnis F, et al. Cancer Res. 2002 Feb 1;62(3):867-74. Cancer Res. 2002. PMID: 11830545
Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration.
Curnis F, Sacchi A, Corti A. Curnis F, et al. J Clin Invest. 2002 Aug;110(4):475-82. doi: 10.1172/JCI15223. J Clin Invest. 2002. PMID: 12189241 Free PMC article.
Chromogranin A protects vessels against tumor necrosis factor alpha-induced vascular leakage.
Ferrero E, Scabini S, Magni E, Foglieni C, Belloni D, Colombo B, Curnis F, Villa A, Ferrero ME, Corti A. Ferrero E, et al. Among authors: curnis f. FASEB J. 2004 Mar;18(3):554-6. doi: 10.1096/fj.03-0922fje. Epub 2004 Jan 20. FASEB J. 2004. PMID: 14734634
Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity.
Curnis F, Gasparri A, Sacchi A, Longhi R, Corti A. Curnis F, et al. Cancer Res. 2004 Jan 15;64(2):565-71. doi: 10.1158/0008-5472.can-03-1753. Cancer Res. 2004. PMID: 14744770
Crucial role for interferon gamma in the synergism between tumor vasculature-targeted tumor necrosis factor alpha (NGR-TNF) and doxorubicin.
Sacchi A, Gasparri A, Curnis F, Bellone M, Corti A. Sacchi A, et al. Among authors: curnis f. Cancer Res. 2004 Oct 1;64(19):7150-5. doi: 10.1158/0008-5472.CAN-04-1445. Cancer Res. 2004. PMID: 15466213
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