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Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy.
Hudson N, Celkova L, Hopkins A, Greene C, Storti F, Ozaki E, Fahey E, Theodoropoulou S, Kenna PF, Humphries MM, Curtis AM, Demmons E, Browne A, Liddie S, Lawrence MS, Grimm C, Cahill MT, Humphries P, Doyle SL, Campbell M. Hudson N, et al. Among authors: curtis am. JCI Insight. 2019 Aug 8;4(15):e130273. doi: 10.1172/jci.insight.130273. eCollection 2019 Aug 8. JCI Insight. 2019. PMID: 31391341 Free PMC article.
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1.
Curtis AM, Fagundes CT, Yang G, Palsson-McDermott EM, Wochal P, McGettrick AF, Foley NH, Early JO, Chen L, Zhang H, Xue C, Geiger SS, Hokamp K, Reilly MP, Coogan AN, Vigorito E, FitzGerald GA, O'Neill LA. Curtis AM, et al. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7231-6. doi: 10.1073/pnas.1501327112. Epub 2015 May 20. Proc Natl Acad Sci U S A. 2015. PMID: 25995365 Free PMC article.
Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.
Early JO, Menon D, Wyse CA, Cervantes-Silva MP, Zaslona Z, Carroll RG, Palsson-McDermott EM, Angiari S, Ryan DG, Corcoran SE, Timmons G, Geiger SS, Fitzpatrick DJ, O'Connell D, Xavier RJ, Hokamp K, O'Neill LAJ, Curtis AM. Early JO, et al. Among authors: curtis am. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8460-E8468. doi: 10.1073/pnas.1800431115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127006 Free PMC article.
Immunometabolism around the Clock.
Carroll RG, Timmons GA, Cervantes-Silva MP, Kennedy OD, Curtis AM. Carroll RG, et al. Among authors: curtis am. Trends Mol Med. 2019 Jul;25(7):612-625. doi: 10.1016/j.molmed.2019.04.013. Epub 2019 May 29. Trends Mol Med. 2019. PMID: 31153819 Review.
Immunometabolism: Is it under the eye of the clock?
Early JO, Curtis AM. Early JO, et al. Among authors: curtis am. Semin Immunol. 2016 Oct;28(5):478-490. doi: 10.1016/j.smim.2016.10.006. Epub 2016 Nov 21. Semin Immunol. 2016. PMID: 27884543 Review.
91 results