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Increased confidence in large-scale phosphoproteomics data by complementary mass spectrometric techniques and matching of phosphopeptide data sets.
Alcolea MP, Kleiner O, Cutillas PR. Alcolea MP, et al. Among authors: cutillas pr. J Proteome Res. 2009 Aug;8(8):3808-15. doi: 10.1021/pr800955n. J Proteome Res. 2009. PMID: 19537829
A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity.
Kostaras E, Kaserer T, Lazaro G, Heuss SF, Hussain A, Casado P, Hayes A, Yandim C, Palaskas N, Yu Y, Schwartz B, Raynaud F, Chung YL, Cutillas PR, Vivanco I. Kostaras E, et al. Among authors: cutillas pr. Br J Cancer. 2020 May 22. doi: 10.1038/s41416-020-0889-4. Online ahead of print. Br J Cancer. 2020. PMID: 32439931
Cancer associated fibroblast FAK regulates malignant cell metabolism.
Demircioglu F, Wang J, Candido J, Costa ASH, Casado P, de Luxan Delgado B, Reynolds LE, Gomez-Escudero J, Newport E, Rajeeve V, Baker AM, Roy-Luzarraga M, Graham TA, Foster J, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Balkwill FR, Sosabowski J, Cutillas PR, Frezza C, Sancho P, Hodivala-Dilke K. Demircioglu F, et al. Among authors: cutillas pr. Nat Commun. 2020 Mar 10;11(1):1290. doi: 10.1038/s41467-020-15104-3. Nat Commun. 2020. PMID: 32157087 Free PMC article.
Detection and analysis of urinary peptides by on-line liquid chromatography and mass spectrometry: application to patients with renal Fanconi syndrome.
Cutillas PR, Norden AG, Cramer R, Burlingame AL, Unwin RJ. Cutillas PR, et al. Clin Sci (Lond). 2003 May;104(5):483-90. doi: 10.1042/CS20020342. Clin Sci (Lond). 2003. PMID: 12529166
The urinary proteome in Fanconi syndrome implies specificity in the reabsorption of proteins by renal proximal tubule cells.
Cutillas PR, Chalkley RJ, Hansen KC, Cramer R, Norden AG, Waterfield MD, Burlingame AL, Unwin RJ. Cutillas PR, et al. Am J Physiol Renal Physiol. 2004 Sep;287(3):F353-64. doi: 10.1152/ajprenal.00018.2004. Epub 2004 May 12. Am J Physiol Renal Physiol. 2004. PMID: 15140760
Proteomic strategies and their application in studies of renal function.
Cutillas P, Burlingame A, Unwin R. Cutillas P, et al. News Physiol Sci. 2004 Jun;19:114-9. doi: 10.1152/nips.01515.2003. News Physiol Sci. 2004. PMID: 15143205 Review.
Quantification of gel-separated proteins and their phosphorylation sites by LC-MS using unlabeled internal standards: analysis of phosphoprotein dynamics in a B cell lymphoma cell line.
Cutillas PR, Geering B, Waterfield MD, Vanhaesebroeck B. Cutillas PR, et al. Mol Cell Proteomics. 2005 Aug;4(8):1038-51. doi: 10.1074/mcp.M500078-MCP200. Epub 2005 May 5. Mol Cell Proteomics. 2005. PMID: 15879432
Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry.
Cutillas PR, Khwaja A, Graupera M, Pearce W, Gharbi S, Waterfield M, Vanhaesebroeck B. Cutillas PR, et al. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):8959-64. doi: 10.1073/pnas.0602101103. Epub 2006 Jun 2. Proc Natl Acad Sci U S A. 2006. PMID: 16751276 Free PMC article.
Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers.
Geering B, Cutillas PR, Nock G, Gharbi SI, Vanhaesebroeck B. Geering B, et al. Among authors: cutillas pr. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7809-14. doi: 10.1073/pnas.0700373104. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2007. PMID: 17470792 Free PMC article.
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