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Cellular bioenergetics as a target for obesity therapy.
Tseng YH, Cypess AM, Kahn CR. Tseng YH, et al. Among authors: cypess am. Nat Rev Drug Discov. 2010 Jun;9(6):465-82. doi: 10.1038/nrd3138. Nat Rev Drug Discov. 2010. PMID: 20514071 Free PMC article. Review.
Identification and importance of brown adipose tissue in adult humans.
Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, Kuo FC, Palmer EL, Tseng YH, Doria A, Kolodny GM, Kahn CR. Cypess AM, et al. N Engl J Med. 2009 Apr 9;360(15):1509-17. doi: 10.1056/NEJMoa0810780. N Engl J Med. 2009. PMID: 19357406 Free PMC article.
Brown fat as a therapy for obesity and diabetes.
Cypess AM, Kahn CR. Cypess AM, et al. Curr Opin Endocrinol Diabetes Obes. 2010 Apr;17(2):143-9. doi: 10.1097/MED.0b013e328337a81f. Curr Opin Endocrinol Diabetes Obes. 2010. PMID: 20160646 Free PMC article. Review.
Insulin enhances glucose-stimulated insulin secretion in healthy humans.
Bouche C, Lopez X, Fleischman A, Cypess AM, O'Shea S, Stefanovski D, Bergman RN, Rogatsky E, Stein DT, Kahn CR, Kulkarni RN, Goldfine AB. Bouche C, et al. Among authors: cypess am. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4770-5. doi: 10.1073/pnas.1000002107. Epub 2010 Feb 22. Proc Natl Acad Sci U S A. 2010. PMID: 20176932 Free PMC article. Clinical Trial.
Cold but not sympathomimetics activates human brown adipose tissue in vivo.
Cypess AM, Chen YC, Sze C, Wang K, English J, Chan O, Holman AR, Tal I, Palmer MR, Kolodny GM, Kahn CR. Cypess AM, et al. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10001-5. doi: 10.1073/pnas.1207911109. Epub 2012 Jun 4. Proc Natl Acad Sci U S A. 2012. PMID: 22665804 Free PMC article.
90 results