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BCL-2 family antagonists for cancer therapy.
Lessene G, Czabotar PE, Colman PM. Lessene G, et al. Among authors: czabotar pe. Nat Rev Drug Discov. 2008 Dec;7(12):989-1000. doi: 10.1038/nrd2658. Nat Rev Drug Discov. 2008. PMID: 19043450 Review.
Structural insights into the degradation of Mcl-1 induced by BH3 domains.
Czabotar PE, Lee EF, van Delft MF, Day CL, Smith BJ, Huang DC, Fairlie WD, Hinds MG, Colman PM. Czabotar PE, et al. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6217-22. doi: 10.1073/pnas.0701297104. Epub 2007 Mar 27. Proc Natl Acad Sci U S A. 2007. PMID: 17389404 Free PMC article.
Bax activation by Bim?
Czabotar PE, Colman PM, Huang DC. Czabotar PE, et al. Cell Death Differ. 2009 Sep;16(9):1187-91. doi: 10.1038/cdd.2009.83. Epub 2009 Jun 26. Cell Death Differ. 2009. PMID: 19557009 Review.
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