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Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)(+) TH2/TH1 cell imbalance, whereas adults acquire CLA(+) TH22/TC22 cell subsets.
Czarnowicki T, Esaki H, Gonzalez J, Malajian D, Shemer A, Noda S, Talasila S, Berry A, Gray J, Becker L, Estrada Y, Xu H, Zheng X, Suárez-Fariñas M, Krueger JG, Paller AS, Guttman-Yassky E. Czarnowicki T, et al. J Allergy Clin Immunol. 2015 Oct;136(4):941-951.e3. doi: 10.1016/j.jaci.2015.05.049. Epub 2015 Aug 1. J Allergy Clin Immunol. 2015. PMID: 26242300 Free PMC article.
Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response.
Dhingra N, Shemer A, Correa da Rosa J, Rozenblit M, Fuentes-Duculan J, Gittler JK, Finney R, Czarnowicki T, Zheng X, Xu H, Estrada YD, Cardinale I, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E. Dhingra N, et al. Among authors: czarnowicki t. J Allergy Clin Immunol. 2014 Aug;134(2):362-72. doi: 10.1016/j.jaci.2014.03.009. Epub 2014 Apr 25. J Allergy Clin Immunol. 2014. PMID: 24768652
Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathology.
Khattri S, Shemer A, Rozenblit M, Dhingra N, Czarnowicki T, Finney R, Gilleaudeau P, Sullivan-Whalen M, Zheng X, Xu H, Cardinale I, de Guzman Strong C, Gonzalez J, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E. Khattri S, et al. Among authors: czarnowicki t. J Allergy Clin Immunol. 2014 Jun;133(6):1626-34. doi: 10.1016/j.jaci.2014.03.003. Epub 2014 Apr 29. J Allergy Clin Immunol. 2014. PMID: 24786238 Free PMC article.
Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin.
Correa da Rosa J, Malajian D, Shemer A, Rozenblit M, Dhingra N, Czarnowicki T, Khattri S, Ungar B, Finney R, Xu H, Zheng X, Estrada YD, Peng X, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E. Correa da Rosa J, et al. Among authors: czarnowicki t. J Allergy Clin Immunol. 2015 Mar;135(3):712-20. doi: 10.1016/j.jaci.2014.11.017. Epub 2015 Jan 10. J Allergy Clin Immunol. 2015. PMID: 25583101
Severe atopic dermatitis is characterized by selective expansion of circulating TH2/TC2 and TH22/TC22, but not TH17/TC17, cells within the skin-homing T-cell population.
Czarnowicki T, Gonzalez J, Shemer A, Malajian D, Xu H, Zheng X, Khattri S, Gilleaudeau P, Sullivan-Whalen M, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E. Czarnowicki T, et al. J Allergy Clin Immunol. 2015 Jul;136(1):104-115.e7. doi: 10.1016/j.jaci.2015.01.020. Epub 2015 Mar 3. J Allergy Clin Immunol. 2015. PMID: 25748064
Petrolatum: Barrier repair and antimicrobial responses underlying this "inert" moisturizer.
Czarnowicki T, Malajian D, Khattri S, Correa da Rosa J, Dutt R, Finney R, Dhingra N, Xiangyu P, Xu H, Estrada YD, Zheng X, Gilleaudeau P, Sullivan-Whalen M, Suaréz-Fariñas M, Shemer A, Krueger JG, Guttman-Yassky E. Czarnowicki T, et al. J Allergy Clin Immunol. 2016 Apr;137(4):1091-1102.e7. doi: 10.1016/j.jaci.2015.08.013. Epub 2015 Oct 1. J Allergy Clin Immunol. 2016. PMID: 26431582 Clinical Trial.
Diverse activation and differentiation of multiple B-cell subsets in patients with atopic dermatitis but not in patients with psoriasis.
Czarnowicki T, Gonzalez J, Bonifacio KM, Shemer A, Xiangyu P, Kunjravia N, Malajian D, Fuentes-Duculan J, Esaki H, Noda S, Estrada Y, Xu H, Zheng X, Krueger JG, Guttman-Yassky E. Czarnowicki T, et al. J Allergy Clin Immunol. 2016 Jan;137(1):118-129.e5. doi: 10.1016/j.jaci.2015.08.027. Epub 2015 Oct 5. J Allergy Clin Immunol. 2016. PMID: 26441226
47 results