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The gut microbiome-prostate cancer crosstalk is modulated by dietary polyunsaturated long-chain fatty acids.
Lachance G, Robitaille K, Laaraj J, Gevariya N, Varin TV, Feldiorean A, Gaignier F, Julien IB, Xu HW, Hallal T, Pelletier JF, Bouslama S, Boufaied N, Derome N, Bergeron A, Ellis L, Piccirillo CA, Raymond F, Fradet Y, Labbé DP, Marette A, Fradet V. Lachance G, et al. Nat Commun. 2024 Apr 23;15(1):3431. doi: 10.1038/s41467-024-45332-w. Nat Commun. 2024. PMID: 38654015
Improved quality of life and psychological symptoms following mindfulness and cognitive rehabilitation in multiple sclerosis and their mediating role for cognition: a randomized controlled trial.
Nauta IM, van Dam M, Bertens D, Kessels RPC, Fasotti L, Uitdehaag BMJ, Speckens AEM, de Jong BA. Nauta IM, et al. J Neurol. 2024 Apr 23. doi: 10.1007/s00415-024-12327-y. Online ahead of print. J Neurol. 2024. PMID: 38653820
RESULTS: MBCT positively affected depressive symptoms (Cohen's d (d) = -0.46), fatigue (d = -0.39), brooding (d = -0.34), mindfulness skills (d = 0.49), and mental QoL (d = -0.73) at post-treatment. Effects on mindfulness skills remained …
RESULTS: MBCT positively affected depressive symptoms (Cohen's d (d) = -0.46), fatigue (d = -0.39), brooding (d …
Exome sequencing in extreme altitude mountaineers identifies pathogenic variants in RTEL1 and COL6A1 previously associated with respiratory failure.
Maksiutenko EM, Merkureva V, Barbitoff YA, Tsay VV, Aseev MV, Glotov AS, Glotov OS. Maksiutenko EM, et al. Physiol Rep. 2024 Apr;12(8):e16015. doi: 10.14814/phy2.16015. Physiol Rep. 2024. PMID: 38653581
To our surprise, we identified two putative loss-of-function variants, rs1385101139 in RTEL1 and rs1002726737 in COL6A1 in two extremely high altitude (personal record of more than 8500 m) professional climbers. Both variants can be interpreted as pathogenic according to m …
To our surprise, we identified two putative loss-of-function variants, rs1385101139 in RTEL1 and rs1002726737 in COL6A1 in two extremely hig …
Low-dose BPA-induced neuronal energy metabolism dysfunction and apoptosis mediated by PINK1/parkin mitophagy pathway in juvenile rats.
Meng L, Ouyang Z, Chen Y, Huang C, Yu Y, Fan R. Meng L, et al. Sci Total Environ. 2024 Apr 21:172655. doi: 10.1016/j.scitotenv.2024.172655. Online ahead of print. Sci Total Environ. 2024. PMID: 38653419
In vitro, hippocampal neurons derived from neonatal rats of different genders were exposed to 1-100 nM and 100 muM BPA, autophagy activator Rapa and inhibitor 3-MA for 7 d. The results suggested that even nanomolar BPA (1-100 nM) disturbed Ca(2+) homeostasis and damaged th …
In vitro, hippocampal neurons derived from neonatal rats of different genders were exposed to 1-100 nM and 100 muM BPA, autophagy activator …
Vergence-Accommodation Conflict: Increased Presbyopia in Virtual Reality.
Huang YY, Menozzi M, Lee CY. Huang YY, et al. Klin Monbl Augenheilkd. 2024 Apr;241(4):540-544. doi: 10.1055/a-2237-2840. Epub 2024 Apr 23. Klin Monbl Augenheilkd. 2024. PMID: 38653312 English.
BACKGROUND: Performance and symptoms in completing a visual search task on a PC monitor and using a head-mounted display (HMD) were compared for different viewing conditions and between users of different ages. PATIENTS AND METHODS: Twenty-three young (M = 30 y, SD = 7 y) …
BACKGROUND: Performance and symptoms in completing a visual search task on a PC monitor and using a head-mounted display (HMD) were compared …
Gastrointestinal response to the early administration of antimicrobial agents in growing turkeys infected with Escherichia coli.
Mikulski D, Juśkiewicz J, Ognik K, Fotschki B, Tykałowski B, Jankowski J. Mikulski D, et al. Poult Sci. 2024 Apr 3;103(6):103720. doi: 10.1016/j.psj.2024.103720. Online ahead of print. Poult Sci. 2024. PMID: 38652949
Experiment 1 lasted 21 d, and turkeys in groups E, D, and M were infected with APEC on d 15. Experiment 2 lasted 56 d, and it had a factorial arrangement of treatments where birds in groups E, D, and M were infected with APEC on …
Experiment 1 lasted 21 d, and turkeys in groups E, D, and M were infected with APEC on d 15. Experiment 2 lasted …
Strong linkage between benthic oxygen uptake and bacterial tetraether lipids in deep-sea trench regions.
Xiao W, Xu Y, Canfield DE, Wenzhöfer F, Zhang C, Glud RN. Xiao W, et al. Nat Commun. 2024 Apr 23;15(1):3439. doi: 10.1038/s41467-024-47660-3. Nat Commun. 2024. PMID: 38653759
Here, we investigated brGDGTs in sediments from three deep-sea regions (4045 to 10,100 m water depth) dominated by three respective trench systems and integrated the results with in situ oxygen microprofile data. ...
Here, we investigated brGDGTs in sediments from three deep-sea regions (4045 to 10,100 m water depth) dominated by three respective t …
Pembrolizumab Plus Binimetinib With or Without Chemotherapy for MSS/pMMR Metastatic Colorectal Cancer: Outcomes From KEYNOTE-651 Cohorts A, C, and E.
Chen EX, Kavan P, Tehfe M, Kortmansky JS, Sawyer MB, Chiorean EG, Lieu CH, Polite B, Wong L, Fakih M, Spencer K, Chaves J, Li C, Leconte P, Adelberg D, Kim R. Chen EX, et al. Clin Colorectal Cancer. 2024 Apr 1:S1533-0028(24)00024-0. doi: 10.1016/j.clcc.2024.03.002. Online ahead of print. Clin Colorectal Cancer. 2024. PMID: 38653648
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