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Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.
Sobotta S, Raue A, Huang X, Vanlier J, Jünger A, Bohl S, Albrecht U, Hahnel MJ, Wolf S, Mueller NS, D'Alessandro LA, Mueller-Bohl S, Boehm ME, Lucarelli P, Bonefas S, Damm G, Seehofer D, Lehmann WD, Rose-John S, van der Hoeven F, Gretz N, Theis FJ, Ehlting C, Bode JG, Timmer J, Schilling M, Klingmüller U. Sobotta S, et al. Among authors: d alessandro la. Front Physiol. 2017 Oct 9;8:775. doi: 10.3389/fphys.2017.00775. eCollection 2017. Front Physiol. 2017. PMID: 29062282 Free PMC article.
Hepatocellular carcinoma: a systems biology perspective.
D'Alessandro LA, Meyer R, Klingmüller U. D'Alessandro LA, et al. Front Physiol. 2013 Feb 25;4:28. doi: 10.3389/fphys.2013.00028. eCollection 2013. Front Physiol. 2013. PMID: 23444340 Free PMC article.
Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation.
Iwamoto N, D'Alessandro LA, Depner S, Hahn B, Kramer BA, Lucarelli P, Vlasov A, Stepath M, Böhm ME, Deharde D, Damm G, Seehofer D, Lehmann WD, Klingmüller U, Schilling M. Iwamoto N, et al. Among authors: d alessandro la. Sci Signal. 2016 Feb 2;9(413):ra13. doi: 10.1126/scisignal.aab1967. Sci Signal. 2016. PMID: 26838549
Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation.
Hammad S, Ogris C, Othman A, Erdoesi P, Schmidt-Heck W, Biermayer I, Helm B, Gao Y, Piorońska W, Holland CH, D'Alessandro LA, de la Torre C, Sticht C, Al Aoua S, Theis FJ, Bantel H, Ebert MP, Klingmüller U, Hengstler JG, Dooley S, Mueller NS. Hammad S, et al. Among authors: d alessandro la. Cell Death Dis. 2023 Jul 12;14(7):414. doi: 10.1038/s41419-023-05855-4. Cell Death Dis. 2023. PMID: 37438332 Free PMC article.
20 results