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Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina D, Settembre C, Gavina M, Pulze L, Giardino I, Pettoello-Mantovani M, D'Apolito M, Guido S, Masliah E, Spencer B, Quaratino S, Raia V, Ballabio A, Maiuri L. Luciani A, et al. Nat Cell Biol. 2010 Sep;12(9):863-75. doi: 10.1038/ncb2090. Epub 2010 Aug 15. Nat Cell Biol. 2010. PMID: 20711182
Stimulation of β2-adrenergic receptor increases CFTR function and decreases ATP levels in murine hematopoietic stem/progenitor cells.
Trotta T, Guerra L, Piro D, d'Apolito M, Piccoli C, Porro C, Giardino I, Lepore S, Castellani S, Di Gioia S, Petrella A, Maffione AB, Casavola V, Capitanio N, Conese M. Trotta T, et al. J Cyst Fibros. 2015 Jan;14(1):26-33. doi: 10.1016/j.jcf.2014.08.005. Epub 2014 Aug 29. J Cyst Fibros. 2015. PMID: 25178873 Free article.
Urea-induced ROS cause endothelial dysfunction in chronic renal failure.
D'Apolito M, Du X, Pisanelli D, Pettoello-Mantovani M, Campanozzi A, Giacco F, Maffione AB, Colia AL, Brownlee M, Giardino I. D'Apolito M, et al. Atherosclerosis. 2015 Apr;239(2):393-400. doi: 10.1016/j.atherosclerosis.2015.01.034. Epub 2015 Jan 31. Atherosclerosis. 2015. PMID: 25682038 Free PMC article.
Genetic analysis of Italian patients with congenital tufting enteropathy.
d'Apolito M, Pisanelli D, Faletra F, Giardino I, Gigante M, Pettoello-Mantovani M, Goulet O, Gasparini P, Campanozzi A. d'Apolito M, et al. World J Pediatr. 2016 May;12(2):219-24. doi: 10.1007/s12519-015-0070-y. Epub 2015 Dec 18. World J Pediatr. 2016. PMID: 26684320
70 results