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The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells.
Ramos-Torres Á, Bort A, Morell C, Rodríguez-Henche N, Díaz-Laviada I. Ramos-Torres Á, et al. Oncotarget. 2016 Jan 12;7(2):1569-83. doi: 10.18632/oncotarget.6415. Oncotarget. 2016. PMID: 26625315 Free PMC article.
Regulation of nerve growth factor secretion and mRNA expression by bacterial lipopolysaccharide in primary cultures of rat astrocytes.
Galve-Roperh I, Malpartida JM, Haro A, Brachet P, Díaz-Laviada I. Galve-Roperh I, et al. J Neurosci Res. 1997 Sep 1;49(5):569-75. doi: 10.1002/(SICI)1097-4547(19970901)49:5<569::AID-JNR7>3.0.CO;2-9. J Neurosci Res. 1997. PMID: 9302078
Delta9-tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor-independent mechanism.
Ruiz L, Miguel A, Díaz-Laviada I. Ruiz L, et al. FEBS Lett. 1999 Sep 24;458(3):400-4. doi: 10.1016/s0014-5793(99)01073-x. FEBS Lett. 1999. PMID: 10570948
delta(9)-Tetrahydrocannabinol increases nerve growth factor production by prostate PC-3 cells. Involvement of CB1 cannabinoid receptor and Raf-1.
Velasco L, Ruiz L, Sánchez MG, Díaz-Laviada I. Velasco L, et al. Eur J Biochem. 2001 Feb;268(3):531-5. doi: 10.1046/j.1432-1327.2001.01884.x. Eur J Biochem. 2001. PMID: 11168391
Activation of phosphoinositide 3-kinase/PKB pathway by CB(1) and CB(2) cannabinoid receptors expressed in prostate PC-3 cells. Involvement in Raf-1 stimulation and NGF induction.
Sánchez MG, Ruiz-Llorente L, Sánchez AM, Díaz-Laviada I. Sánchez MG, et al. Cell Signal. 2003 Sep;15(9):851-9. doi: 10.1016/s0898-6568(03)00036-6. Cell Signal. 2003. PMID: 12834810
Enhancement of androgen receptor expression induced by (R)-methanandamide in prostate LNCaP cells.
Sánchez MG, Sánchez AM, Ruiz-Llorente L, Díaz-Laviada I. Sánchez MG, et al. FEBS Lett. 2003 Dec 18;555(3):561-6. doi: 10.1016/s0014-5793(03)01349-8. FEBS Lett. 2003. PMID: 14675774
Characterization of an anandamide degradation system in prostate epithelial PC-3 cells: synthesis of new transporter inhibitors as tools for this study.
Ruiz-Llorente L, Ortega-Gutiérrez S, Viso A, Sánchez MG, Sánchez AM, Fernández C, Ramos JA, Hillard C, Lasunción MA, López-Rodríguez ML, Díaz-Laviada I. Ruiz-Llorente L, et al. Br J Pharmacol. 2004 Feb;141(3):457-67. doi: 10.1038/sj.bjp.0705628. Epub 2004 Jan 12. Br J Pharmacol. 2004. PMID: 14718261 Free PMC article.
Vasoactive intestinal peptide (VIP) induces c-fos expression in LNCaP prostate cancer cells through a mechanism that involves Ca2+ signalling. Implications in angiogenesis and neuroendocrine differentiation.
Collado B, Sánchez MG, Díaz-Laviada I, Prieto JC, Carmena MJ. Collado B, et al. Biochim Biophys Acta. 2005 Jun 30;1744(2):224-33. doi: 10.1016/j.bbamcr.2005.04.009. Biochim Biophys Acta. 2005. PMID: 15921770
Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin.
Sánchez AM, Sánchez MG, Malagarie-Cazenave S, Olea N, Díaz-Laviada I. Sánchez AM, et al. Apoptosis. 2006 Jan;11(1):89-99. doi: 10.1007/s10495-005-3275-z. Apoptosis. 2006. PMID: 16374544
Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation.
Sánchez AM, Malagarie-Cazenave S, Olea N, Vara D, Chiloeches A, Díaz-Laviada I. Sánchez AM, et al. Apoptosis. 2007 Nov;12(11):2013-24. doi: 10.1007/s10495-007-0119-z. Apoptosis. 2007. PMID: 17828457
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