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Dominant negative effectors of heparin affin regulatory peptide (HARP) angiogenic and transforming activities.
Bernard-Pierrot I, Delbé J, Rouet V, Vigny M, Kerros ME, Caruelle D, Raulais D, Barritault D, Courty J, Milhiet PE. Bernard-Pierrot I, et al. Among authors: caruelle d. J Biol Chem. 2002 Aug 30;277(35):32071-7. doi: 10.1074/jbc.M202747200. Epub 2002 Jun 17. J Biol Chem. 2002. PMID: 12070152 Free article.
Recently, we have demonstrated that the C-terminal residues 111-136 of HARP are required for its mitogenic and transforming activities (Bernard-Pierrot, I., Delbe, J., Caruelle, D., Barritault, D., Courty, J., and Milhiet, P. E. (2001) J. Biol. Chem. 276, 12228-1223 …
Recently, we have demonstrated that the C-terminal residues 111-136 of HARP are required for its mitogenic and transforming activities (Bern …
A synthetic glycosaminoglycan mimetic binds vascular endothelial growth factor and modulates angiogenesis.
Rouet V, Hamma-Kourbali Y, Petit E, Panagopoulou P, Katsoris P, Barritault D, Caruelle JP, Courty J. Rouet V, et al. Among authors: caruelle jp. J Biol Chem. 2005 Sep 23;280(38):32792-800. doi: 10.1074/jbc.M504492200. Epub 2005 Jul 13. J Biol Chem. 2005. PMID: 16014624 Free article.
In a previous study, we showed that in situ injection of glycosaminoglycan mimetics called RGTAs (ReGeneraTing Agents) enhanced neovascularization after skeletal muscular ischemia (Desgranges, P., Barbaud, C., Caruelle, J. P., Barritault, D., and Gautron, J. (1999) FASEB J …
In a previous study, we showed that in situ injection of glycosaminoglycan mimetics called RGTAs (ReGeneraTing Agents) enhanced neovasculari …
New concepts in tissue repair: skin as an example.
Meddahi A, Caruelle JP, Gold L, Rosso Y, Barritault D. Meddahi A, et al. Among authors: caruelle jp. Diabetes Metab. 1996 Jul;22(4):274-8. Diabetes Metab. 1996. PMID: 8767175 Review.
Controlled sulfatation of natural anionic bacterial polysaccharides can yield agents with specific regenerating activity in vivo.
Petit E, Papy-Garcia D, Muller G, Courtois B, Caruelle JP, Courtois J. Petit E, et al. Among authors: caruelle jp. Biomacromolecules. 2004 Mar-Apr;5(2):445-52. doi: 10.1021/bm034257b. Biomacromolecules. 2004. PMID: 15003004
Glucuronan (GA), a linear homopolysaccharide of -->4)-beta-D-GlcpA-(1--> residues partially acetylated at the C-3 and/or the C-2 position, and glucoglucuronan (GGA), a linear heteropolysaccharide of -->3)-beta-D-GlcpA-(1-->4)-beta-D-Glcp-(1--> …
Glucuronan (GA), a linear homopolysaccharide of -->4)-beta-D-GlcpA-(1--> residues partially acetylated at the C-3 and/or the C- …
Human plasmin enzymatic activity is inhibited by chemically modified dextrans.
Ledoux D, Papy-Garcia D, Escartin Q, Sagot MA, Cao Y, Barritault D, Courtois J, Hornebeck W, Caruelle JP. Ledoux D, et al. Among authors: caruelle jp. J Biol Chem. 2000 Sep 22;275(38):29383-90. doi: 10.1074/jbc.M000837200. J Biol Chem. 2000. PMID: 10889187 Free article.
Analysis with an optical biosensor confirmed the high affinity of RG1192 for plasmin and revealed that this polymer equally binds plasminogen with a similar affinity (K(d) = 3 x 10(-8) m). Competitive experiments carried out with 6-aminohexanoic acid and kringle proteolyti …
Analysis with an optical biosensor confirmed the high affinity of RG1192 for plasmin and revealed that this polymer equally binds plasminoge …
Inhibition of the mitogenic, angiogenic and tumorigenic activities of pleiotrophin by a synthetic peptide corresponding to its C-thrombospondin repeat-I domain.
Hamma-Kourbali Y, Bernard-Pierrot I, Heroult M, Dalle S, Caruelle D, Milhiet PE, Fernig DG, Delbé J, Courty J. Hamma-Kourbali Y, et al. Among authors: caruelle d. J Cell Physiol. 2008 Jan;214(1):250-9. doi: 10.1002/jcp.21191. J Cell Physiol. 2008. PMID: 17607711
P(65-97) but not P(13-39) inhibited the binding of PTN and to a lesser extent of FGF-2 to heparin using an immunoassay and an optical biosensor assay and bound directly to heparin with a K(d) of 120 nM. These findings suggest that P(65-97), containing amino acids 65-97 of …
P(65-97) but not P(13-39) inhibited the binding of PTN and to a lesser extent of FGF-2 to heparin using an immunoassay and an optical biosen …
13 results