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1961 1
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1985 1
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2012 3
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2016 2
2017 1
2018 1
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Promoting epithelial-to-mesenchymal transition by D-kynurenine via activating aryl hydrocarbon receptor.
Duan Z, Li Y, Li L. Duan Z, et al. Mol Cell Biochem. 2018 Nov;448(1-2):165-173. doi: 10.1007/s11010-018-3323-y. Epub 2018 Feb 13. Mol Cell Biochem. 2018. PMID: 29442266
However, the effects of D-enantiomer of kynurenine, D-kynurenine (D-Kyn), on metastasis are still unclear. ...Most importantly, the evidences-10/40 M D-Kyn-induced up-regulation of CYP1A1, 10 M D-Kyn-induced increase of nuclear tra …
However, the effects of D-enantiomer of kynurenine, D-kynurenine (D-Kyn), on metastasis are still unclear …
A method for the determination of D-kynurenine in biological tissues.
Wang XD, Horning KJ, Notarangelo FM, Schwarcz R. Wang XD, et al. Anal Bioanal Chem. 2013 Dec;405(30):9747-54. doi: 10.1007/s00216-013-7399-7. Epub 2013 Oct 26. Anal Bioanal Chem. 2013. PMID: 24158577
D-kynurenine (D-KYN), a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3-hydroxykynurenine, two neuroactive compounds that are believed to play a role in the pathophysiology of several neurological and psychiatri
D-kynurenine (D-KYN), a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3
Role of d-amino acid oxidase in the production of kynurenine pathway metabolites from d-tryptophan in mice.
Notarangelo FM, Wang XD, Horning KJ, Schwarcz R. Notarangelo FM, et al. J Neurochem. 2016 Feb;136(4):804-814. doi: 10.1111/jnc.13455. Epub 2016 Jan 13. J Neurochem. 2016. PMID: 26661897 Free PMC article.
The role of the d-enantiomer (d-TRP) in KP metabolism has received little attention so far. d-TRP can be converted to l-TRP by d-amino acid oxidase, and the same enzyme can produce d-kynurenine, a known bioprecursor of KYNA. ...We report …
The role of the d-enantiomer (d-TRP) in KP metabolism has received little attention so far. d-TRP can be converted to l …
Enzymatic transamination of D-kynurenine generates kynurenic acid in rat and human brain.
Pérez-de la Cruz V, Amori L, Sathyasaikumar KV, Wang XD, Notarangelo FM, Wu HQ, Schwarcz R. Pérez-de la Cruz V, et al. J Neurochem. 2012 Mar;120(6):1026-35. doi: 10.1111/j.1471-4159.2012.07653.x. Epub 2012 Feb 2. J Neurochem. 2012. PMID: 22224417 Free PMC article.
In the mammalian brain, the alpha7 nicotinic and NMDA receptor antagonist kynurenic acid is synthesized by irreversible enzymatic transamination of the tryptophan metabolite l-kynurenine. d-kynurenine, too, serves as a bioprecursor of kynurenic acid in severa …
In the mammalian brain, the alpha7 nicotinic and NMDA receptor antagonist kynurenic acid is synthesized by irreversible enzymatic transamina …
Kynurenic acid and 3-hydroxykynurenine production from D-kynurenine in mice.
Wang XD, Notarangelo FM, Wang JZ, Schwarcz R. Wang XD, et al. Brain Res. 2012 May 21;1455:1-9. doi: 10.1016/j.brainres.2012.03.026. Epub 2012 Mar 17. Brain Res. 2012. PMID: 22498176 Free PMC article.
In the mammalian brain as elsewhere, both compounds derive from a common bioprecursor, L-kynurenine (L-KYN). Recent studies in rats demonstrated that D-kynurenine (D-KYN), a metabolite of the bacterial amino acid D-tryptophan, can also function …
In the mammalian brain as elsewhere, both compounds derive from a common bioprecursor, L-kynurenine (L-KYN). Recent studies in rats d …
Biochemical Properties of Human D-Amino Acid Oxidase.
Murtas G, Sacchi S, Valentino M, Pollegioni L. Murtas G, et al. Front Mol Biosci. 2017 Dec 15;4:88. doi: 10.3389/fmolb.2017.00088. eCollection 2017. Front Mol Biosci. 2017. PMID: 29326945 Free PMC article.
D-amino acid oxidase catalyzes the oxidative deamination of D-amino acids. ...Indeed, the flavoenzyme shows a preference for hydrophobic amino acids, some of which are molecules relevant in neurotransmission, i.e., D-kynurenine, D-DOPA, and D
D-amino acid oxidase catalyzes the oxidative deamination of D-amino acids. ...Indeed, the flavoenzyme shows a preference for h
Fluorimetric assay for D-amino acid oxidase activity in rat brain homogenate by using D-kynurenine as a substrate.
Kozaki A, Iwasa S, Hosoda S, Nishiguchi Y, Nakayama M, Ichiba H, Fukushima T. Kozaki A, et al. Biosci Trends. 2012 Oct;6(5):241-7. doi: 10.5582/bst.2012.v6.5.241. Biosci Trends. 2012. PMID: 23229117 Free article.
An easy fluorimetric assay for measuring D-amino acid oxidase (DAAO) activity by using one of the D-amino acids--D-kynurenine (D-KYN)--as a substrate was applied to assess DAAO activity in the cerebrum, cerebellum, and brainstem of Sprague-Dawle …
An easy fluorimetric assay for measuring D-amino acid oxidase (DAAO) activity by using one of the D-amino acids--D-k
Changes in the plasma concentrations of D-kynurenine and kynurenic acid in rats after intraperitoneal administration of tryptophan enantiomers.
Ishii K, Ogaya T, Song Z, Iizuka H, Fukushima T. Ishii K, et al. Chirality. 2010 Nov;22(10):901-6. doi: 10.1002/chir.20850. Chirality. 2010. PMID: 20872665
The time-course profiles of the rat plasma concentrations of D-kynurenine (KYN), L-KYN, and kynurenic acid (KYNA), which are metabolites of D- or L-Trp, were investigated using high-performance liquid chromatography (HPLC) systems that were reported in our pr …
The time-course profiles of the rat plasma concentrations of D-kynurenine (KYN), L-KYN, and kynurenic acid (KYNA), which are m …
Inhibition of D-amino acid oxidase activity by antipsychotic drugs evaluated by a fluorometric assay using D-kynurenine as substrate.
Iwasa S, Tabara H, Song Z, Nakabayashi M, Yokoyama Y, Fukushima T. Iwasa S, et al. Yakugaku Zasshi. 2011;131(7):1111-6. doi: 10.1248/yakushi.131.1111. Yakugaku Zasshi. 2011. PMID: 21720142 Free article.
A facile fluorometric assay using D-kynurenine as a substrate was utilized for evaluating the inhibition of D-amino acid oxidase (DAAO), which is one of the products of a susceptibility gene for schizophrenia, by commercial antipsychotic drugs, namely, chlorp …
A facile fluorometric assay using D-kynurenine as a substrate was utilized for evaluating the inhibition of D-amino aci …
20 results