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DDX51 gene promotes proliferation by activating Wnt/beta-catenin signaling in breast cancer.
Sun W, Cang S, Lv X, Wang P, Lin Q, Zhang Q, Yan Z, Liu Z, Song Y. Sun W, et al. Int J Clin Exp Pathol. 2017 Nov 1;10(11):10892-10900. eCollection 2017. Int J Clin Exp Pathol. 2017. PMID: 31966432 Free PMC article.
And DDX51 gene was shown to promote proliferation in NSCLC. But we firstly reported the abundant expression of DDX51 gene in both the breast cancer tissues and cell lines in this study. And DDX51 expression was shown to be associated with TNM stage and …
And DDX51 gene was shown to promote proliferation in NSCLC. But we firstly reported the abundant expression of DDX51 gene in b …
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.
Bueno R, Stawiski EW, Goldstein LD, Durinck S, De Rienzo A, Modrusan Z, Gnad F, Nguyen TT, Jaiswal BS, Chirieac LR, Sciaranghella D, Dao N, Gustafson CE, Munir KJ, Hackney JA, Chaudhuri A, Gupta R, Guillory J, Toy K, Ha C, Chen YJ, Stinson J, Chaudhuri S, Zhang N, Wu TD, Sugarbaker DJ, de Sauvage FJ, Richards WG, Seshagiri S. Bueno R, et al. Nat Genet. 2016 Apr;48(4):407-16. doi: 10.1038/ng.3520. Epub 2016 Feb 29. Nat Genet. 2016. PMID: 26928227
Through exome analysis, we found BAP1, NF2, TP53, SETD2, DDX3X, ULK2, RYR2, CFAP45, SETDB1 and DDX51 to be significantly mutated (q-score 0.8) in MPMs. We identified recurrent mutations in several genes, including SF3B1 (2%; 4/216) and TRAF7 (2%; 5/216). ...
Through exome analysis, we found BAP1, NF2, TP53, SETD2, DDX3X, ULK2, RYR2, CFAP45, SETDB1 and DDX51 to be significantly mutated (q-s …
Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma via the PI3K/AKT pathway.
Hu DX, Sun QF, Xu L, Lu HD, Zhang F, Li ZM, Zhang MY. Hu DX, et al. World J Gastroenterol. 2022 Jan 28;28(4):464-478. doi: 10.3748/wjg.v28.i4.464. World J Gastroenterol. 2022. PMID: 35125830 Free PMC article.
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent malignancies that seriously threaten people's health worldwide. DEAD-box helicase 51 (DDX51) is a member of the DEAD-box (DDX) RNA helicase family, and drives or inhibits tumor progression i …
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent malignancies that seriously threaten people's health worl …
The DEAD-box RNA helicase 51 controls non-small cell lung cancer proliferation by regulating cell cycle progression via multiple pathways.
Wang X, Liu H, Zhao C, Li W, Xu H, Chen Y. Wang X, et al. Sci Rep. 2016 May 20;6:26108. doi: 10.1038/srep26108. Sci Rep. 2016. PMID: 27198888 Free PMC article.
The genetic regulation of cell cycle progression and cell proliferation plays a role in the growth of non-small cell lung cancer (NSCLC), one of the most common causes of cancer-related mortality. Although DEAD-box RNA helicases are known to play a role in cancer …
The genetic regulation of cell cycle progression and cell proliferation plays a role in the growth of non-small cell lung cancer (NSC …
Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia.
Taylor KH, Pena-Hernandez KE, Davis JW, Arthur GL, Duff DJ, Shi H, Rahmatpanah FB, Sjahputera O, Caldwell CW. Taylor KH, et al. Cancer Res. 2007 Mar 15;67(6):2617-25. doi: 10.1158/0008-5472.CAN-06-3993. Cancer Res. 2007. PMID: 17363581
The methylation status of 10 clones encompassing 11 genes (DCC, DLC-1, DDX51, KCNK2, LRP1B, NKX6-1, NOPE, PCDHGA12, RPIB9, ABCB1, and SLC2A14) identified as differentially methylated between ALL patients and controls was independently verified. Consequently, the methylatio …
The methylation status of 10 clones encompassing 11 genes (DCC, DLC-1, DDX51, KCNK2, LRP1B, NKX6-1, NOPE, PCDHGA12, RPIB9, ABCB1, and …