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BG4 antibody can recognize telomeric G-quadruplexes harboring destabilizing base modifications and lesions.
Nucleic Acids Res. 2024 Feb 28;52(4):1763-1778. doi: 10.1093/nar/gkad1209.
Nucleic Acids Res. 2024.
PMID: 38153143
Free PMC article.
Assembly path dependence of telomeric DNA compaction by TRF1, TIN2, and SA1.
Liu M, Pan H, Kaur P, Wang LJ, Jin M, Detwiler AC, Opresko PL, Tao YJ, Wang H, Riehn R.
Liu M, et al. Among authors: detwiler ac.
Biophys J. 2023 May 16;122(10):1822-1832. doi: 10.1016/j.bpj.2023.04.014. Epub 2023 Apr 20.
Biophys J. 2023.
PMID: 37081787
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Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening.
Barnes RP, de Rosa M, Thosar SA, Detwiler AC, Roginskaya V, Van Houten B, Bruchez MP, Stewart-Ornstein J, Opresko PL.
Barnes RP, et al. Among authors: detwiler ac.
Nat Struct Mol Biol. 2022 Jul;29(7):639-652. doi: 10.1038/s41594-022-00790-y. Epub 2022 Jun 30.
Nat Struct Mol Biol. 2022.
PMID: 35773409
Free PMC article.
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Noncanonical necrosis in 2 different cell types in a Caenorhabditis elegans NAD+ salvage pathway mutant.
Reza RN, Serra ND, Detwiler AC, Hanna-Rose W, Crook M.
Reza RN, et al. Among authors: detwiler ac.
G3 (Bethesda). 2022 Apr 4;12(4):jkac033. doi: 10.1093/g3journal/jkac033.
G3 (Bethesda). 2022.
PMID: 35143646
Free PMC article.
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TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA.
Kaur P, Barnes R, Pan H, Detwiler AC, Liu M, Mahn C, Hall J, Messenger Z, You C, Piehler J, Smart RC, Riehn R, Opresko PL, Wang H.
Kaur P, et al. Among authors: detwiler ac.
Nucleic Acids Res. 2021 Dec 16;49(22):13000-13018. doi: 10.1093/nar/gkab1142.
Nucleic Acids Res. 2021.
PMID: 34883513
Free PMC article.
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Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA.
Pan H, Kaur P, Barnes R, Detwiler AC, Sanford SL, Liu M, Xu P, Mahn C, Tang Q, Hao P, Bhattaram D, You C, Gu X, Lu W, Piehler J, Xu G, Weninger K, Riehn R, Opresko PL, Wang H.
Pan H, et al. Among authors: detwiler ac.
J Biol Chem. 2021 Sep;297(3):101080. doi: 10.1016/j.jbc.2021.101080. Epub 2021 Aug 14.
J Biol Chem. 2021.
PMID: 34403696
Free PMC article.
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Comparative Metabolomic Profiling Reveals That Dysregulated Glycolysis Stemming from Lack of Salvage NAD+ Biosynthesis Impairs Reproductive Development in Caenorhabditis elegans.
Wang W, McReynolds MR, Goncalves JF, Shu M, Dhondt I, Braeckman BP, Lange SE, Kho K, Detwiler AC, Pacella MJ, Hanna-Rose W.
Wang W, et al. Among authors: detwiler ac.
J Biol Chem. 2015 Oct 23;290(43):26163-79. doi: 10.1074/jbc.M115.662916. Epub 2015 Sep 8.
J Biol Chem. 2015.
PMID: 26350462
Free PMC article.
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Paroxysmal fussing in infancy, sometimes called colic.
WESSEL MA, COBB JC, JACKSON EB, HARRIS GS Jr, DETWILER AC.
WESSEL MA, et al. Among authors: detwiler ac.
Pediatrics. 1954 Nov;14(5):421-35.
Pediatrics. 1954.
PMID: 13214956
No abstract available.
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