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Clinical validation of a blood-based liquid biopsy test integrating cell-free DNA quantification and next-generation sequencing for cancer screening in dogs.
Flory A, Ruiz-Perez CA, Clavere-Graciette AG, Rafalko JM, O'Kell AL, Flesner BK, McLennan LM, Hicks SC, Nakashe P, Phelps-Dunn A, DiMarzio LR, Warren CD, Cohen TA, Chibuk J, Chorny I, Grosu DS, Tsui DWY, Tynan JA, Kruglyak KM. Flory A, et al. J Am Vet Med Assoc. 2024 Feb 7:1-9. doi: 10.2460/javma.23.10.0564. Online ahead of print. J Am Vet Med Assoc. 2024. PMID: 38324993
Detection of Age-Related Somatic Alterations in Canine Blood Using Next-Generation Sequencing-Based Liquid Biopsy: An Analysis of over 4800 Dogs.
Kruglyak KM, O'Kell AL, Cohen TA, Marshall MA, Ruiz-Perez CA, Marass F, Tynan JA, Hicks SC, Lytle KM, Phelps-Dunn A, Brandstetter G, Warren CD, DiMarzio LR, Rosentel MC, Wong LK, McLennan LM, Rafalko JM, Grosu DS, Chibuk J, Chorny I, McCleary-Wheeler AL, Flory A, Tsui DWY. Kruglyak KM, et al. Vet Sci. 2023 Jul 11;10(7):455. doi: 10.3390/vetsci10070455. Vet Sci. 2023. PMID: 37505860 Free PMC article.
Clinical experience with next-generation sequencing-based liquid biopsy testing for cancer detection in dogs: a review of 1,500 consecutive clinical cases.
O'Kell AL, Lytle KM, Cohen TA, Wong LK, Sandford E, Rafalko JM, Brandstetter G, DiMarzio LR, Phelps-Dunn A, Rosentel MC, Warren CD, McCleary-Wheeler AL, Fiaux PC, Marass F, Marshall MA, Ruiz-Perez CA, Kruglyak KM, Tynan JA, Hicks SC, Grosu DS, Chibuk J, Chorny I, Tsui DWY, Flory A. O'Kell AL, et al. J Am Vet Med Assoc. 2023 Mar 17;261(6):827-836. doi: 10.2460/javma.22.11.0526. Print 2023 Jun 1. J Am Vet Med Assoc. 2023. PMID: 36965477 Review.
Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of more than 3,000 dogs: Determining the optimal age to initiate cancer screening in canine patients.
Rafalko JM, Kruglyak KM, McCleary-Wheeler AL, Goyal V, Phelps-Dunn A, Wong LK, Warren CD, Brandstetter G, Rosentel MC, DiMarzio L, McLennan LM, O'Kell AL, Cohen TA, Grosu DS, Chibuk J, Tsui DWY, Chorny I, Flory A. Rafalko JM, et al. PLoS One. 2023 Feb 1;18(2):e0280795. doi: 10.1371/journal.pone.0280795. eCollection 2023. PLoS One. 2023. PMID: 36724177 Free PMC article.
Cancer detection in clinical practice and using blood-based liquid biopsy: A retrospective audit of over 350 dogs.
Flory A, McLennan L, Peet B, Kroll M, Stuart D, Brown D, Stuebner K, Phillips B, Coomber BL, Woods JP, Miller M, Tripp CD, Wolf-Ringwall A, Kruglyak KM, McCleary-Wheeler AL, Phelps-Dunn A, Wong LK, Warren CD, Brandstetter G, Rosentel MC, DiMarzio LR, O'Kell AL, Cohen TA, Grosu DS, Chibuk J, Tsui DWY, Chorny I, Rafalko JM. Flory A, et al. J Vet Intern Med. 2023 Jan;37(1):258-267. doi: 10.1111/jvim.16616. Epub 2023 Jan 20. J Vet Intern Med. 2023. PMID: 36661398 Free PMC article.
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