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Year Number of Results
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112 results

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Page 1
Histone post-translational modifications - cause and consequence of genome function.
Millán-Zambrano G, Burton A, Bannister AJ, Schneider R. Millán-Zambrano G, et al. Nat Rev Genet. 2022 Sep;23(9):563-580. doi: 10.1038/s41576-022-00468-7. Epub 2022 Mar 25. Nat Rev Genet. 2022. PMID: 35338361 Review.
Much has been learned since the early 1960s about histone post-translational modifications (PTMs) and how they affect DNA-templated processes at the molecular level. This understanding has been bolstered in the past decade by the identification of new types of histo …
Much has been learned since the early 1960s about histone post-translational modifications (PTMs) and how they affect DNA-template …
Protein-Templated Reactions Using DNA-Antibody Conjugates.
Baranda Pellejero L, Nijenhuis MAD, Ricci F, Gothelf KV. Baranda Pellejero L, et al. Small. 2023 Mar;19(13):e2200971. doi: 10.1002/smll.202200971. Epub 2022 Mar 28. Small. 2023. PMID: 35344264
DNA-templated chemical reactions have found wide applications in drug discovery, programmed multistep synthesis, nucleic acid detection, and targeted drug delivery. ...In this work a system capable of translating protein-protein binding events into a DNA-t …
DNA-templated chemical reactions have found wide applications in drug discovery, programmed multistep synthesis, nucleic acid …
DNA Origami Tessellations.
Tang Y, Liu H, Wang Q, Qi X, Yu L, Šulc P, Zhang F, Yan H, Jiang S. Tang Y, et al. J Am Chem Soc. 2023 Jun 28;145(25):13858-13868. doi: 10.1021/jacs.3c03044. Epub 2023 Jun 17. J Am Chem Soc. 2023. PMID: 37329284
Here, we present a general method for creating DNA origami tiles that grow into tessellation patterns with micrometer-scale order and nanometer-scale precision. ...Both yielded various tiling patterns that rivaled Platonic tilings in size and quality, indicating the robust …
Here, we present a general method for creating DNA origami tiles that grow into tessellation patterns with micrometer-scale order and …
DNA-Templated Fluorescent Nanoclusters for Metal Ions Detection.
Song C, Xu J, Chen Y, Zhang L, Lu Y, Qing Z. Song C, et al. Molecules. 2019 Nov 19;24(22):4189. doi: 10.3390/molecules24224189. Molecules. 2019. PMID: 31752270 Free PMC article. Review.
Additionally, the preparation and applications of DNA-templated fluorescent NCs in these sensing have been widely studied. This review firstly focuses on the properties of DNA-templated fluorescent NCs, and the synthesis of DNA-templated …
Additionally, the preparation and applications of DNA-templated fluorescent NCs in these sensing have been widely studied. Thi …
USP3 promotes DNA damage response and chemotherapy resistance through stabilizing and deubiquitinating SMARCA5 in prostate cancer.
Li S, Xiong S, Li Z, Yang L, Yang H, Xiong J, Pan W, Guo J, Xu S, Fu B. Li S, et al. Cell Death Dis. 2024 Nov 5;15(11):790. doi: 10.1038/s41419-024-07117-3. Cell Death Dis. 2024. PMID: 39500888 Free PMC article.
The chromatin-remodeling enzyme SMARCA5 plays a key role in DNA-templated events including transcription, DNA replication, and DNA repair. Loss of function of the SMARCA5 can cause neurodevelopmental disorder and Williams syndrome. ...Here, we r …
The chromatin-remodeling enzyme SMARCA5 plays a key role in DNA-templated events including transcription, DNA replic …
Chromatin and DNA replication.
MacAlpine DM, Almouzni G. MacAlpine DM, et al. Cold Spring Harb Perspect Biol. 2013 Aug 1;5(8):a010207. doi: 10.1101/cshperspect.a010207. Cold Spring Harb Perspect Biol. 2013. PMID: 23751185 Free PMC article. Review.
Chromatin organization and its dynamics participate in essentially all DNA-templated processes, including transcription, replication, recombination, and repair. Here we will focus mainly on nucleosomal organization and describe the pathways and mechanisms tha …
Chromatin organization and its dynamics participate in essentially all DNA-templated processes, including transcription, re …
Photo-Cross-Linking To Delineate Epigenetic Interactome.
Zhang Z, Lin J, Liu Z, Tian G, Li XM, Jing Y, Li X, Li XD. Zhang Z, et al. J Am Chem Soc. 2022 Nov 23;144(46):20979-20997. doi: 10.1021/jacs.2c06135. Epub 2022 Nov 8. J Am Chem Soc. 2022. PMID: 36346429 Review.
Covalent modifications of DNA and histones are key cellular epigenetic marks to regulate gene functions. Most of these epigenetic marks are added or removed by corresponding enzymes known as writers and erasers, whose catalytic activities normally rely on the presence of c …
Covalent modifications of DNA and histones are key cellular epigenetic marks to regulate gene functions. Most of these epigenetic mar …
Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate.
Franklin R, Zhang B, Frazier J, Chen M, Do BT, Padayao S, Wu K, Vander Heiden MG, Vakoc CR, Roe JS, Ninova M, Murn J, Sykes DB, Cheloufi S. Franklin R, et al. Genes Dev. 2025 May 2;39(9-10):652-675. doi: 10.1101/gad.352316.124. Genes Dev. 2025. PMID: 40240143 Free PMC article.
The manipulation of DNA replication and transcription can be harnessed to control cell fate. Central to the regulation of these DNA-templated processes are histone chaperones, which in turn are emerging as cell fate regulators. ...To directly compare h …
The manipulation of DNA replication and transcription can be harnessed to control cell fate. Central to the regulation of thes …
DNA-Templated Reactions with High Catalytic Efficiency Achieved by a Loss-of-Affinity Principle.
Gluhacevic von Krüchten D, Roth M, Seitz O. Gluhacevic von Krüchten D, et al. J Am Chem Soc. 2022 Jun 22;144(24):10700-10704. doi: 10.1021/jacs.2c03188. Epub 2022 Jun 13. J Am Chem Soc. 2022. PMID: 35696276
Nucleic-acid-templated chemical reactions are currently explored for applications in DNA-encoded drug discovery, nucleic acid diagnostics, and theranostics. Of particular interest are reactions enabling the template to gain catalytic activity, so that enzymatic amplificati …
Nucleic-acid-templated chemical reactions are currently explored for applications in DNA-encoded drug discovery, nucleic acid diagnos …
Synthesis of DNA-Templated Silver Nanoclusters and the Characterization of Their Optical Properties and Biological Activity.
Skelly E, Rolband LA, Beasock D, Afonin KA. Skelly E, et al. Methods Mol Biol. 2023;2709:299-307. doi: 10.1007/978-1-0716-3417-2_21. Methods Mol Biol. 2023. PMID: 37572290 Free PMC article.
DNA-templated silver nanoclusters (DNA-AgNCs) are a unique class of bioinorganic nanomaterials. ...In order to evaluate the DNA-AgNCs for cytotoxic activity, cell viability assays which probe mitochondrial activity were used. ...
DNA-templated silver nanoclusters (DNA-AgNCs) are a unique class of bioinorganic nanomaterials. ...In order to evaluate …
112 results