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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2013 2
2014 6
2015 4
2016 2
2020 0
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11 results
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Development and applications of CRISPR-Cas9 for genome engineering.
Hsu PD, Lander ES, Zhang F. Hsu PD, et al. Cell. 2014 Jun 5;157(6):1262-1278. doi: 10.1016/j.cell.2014.05.010. Cell. 2014. PMID: 24906146 Free PMC article. Review.
CRISPR-Cas9 knockin mice for genome editing and cancer modeling.
Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, Anderson DG, Hacohen N, Regev A, Feng G, Sharp PA, Zhang F. Platt RJ, et al. Cell. 2014 Oct 9;159(2):440-55. doi: 10.1016/j.cell.2014.09.014. Epub 2014 Sep 25. Cell. 2014. PMID: 25263330 Free PMC article.
High-throughput functional genomics using CRISPR-Cas9.
Shalem O, Sanjana NE, Zhang F. Shalem O, et al. Nat Rev Genet. 2015 May;16(5):299-311. doi: 10.1038/nrg3899. Epub 2015 Apr 9. Nat Rev Genet. 2015. PMID: 25854182 Free PMC article. Review.
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F. Konermann S, et al. Nature. 2015 Jan 29;517(7536):583-8. doi: 10.1038/nature14136. Epub 2014 Dec 10. Nature. 2015. PMID: 25494202 Free PMC article.
DNA targeting specificity of RNA-guided Cas9 nucleases.
Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. Hsu PD, et al. Nat Biotechnol. 2013 Sep;31(9):827-32. doi: 10.1038/nbt.2647. Epub 2013 Jul 21. Nat Biotechnol. 2013. PMID: 23873081 Free PMC article.
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.
Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. Nelson CE, et al. Science. 2016 Jan 22;351(6271):403-7. doi: 10.1126/science.aad5143. Epub 2015 Dec 31. Science. 2016. PMID: 26721684 Free PMC article.
Optical control of mammalian endogenous transcription and epigenetic states.
Konermann S, Brigham MD, Trevino A, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F. Konermann S, et al. Nature. 2013 Aug 22;500(7463):472-476. doi: 10.1038/nature12466. Epub 2013 Aug 23. Nature. 2013. PMID: 23877069 Free PMC article.
Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.
Zhou Y, Kaiser T, Monteiro P, Zhang X, Van der Goes MS, Wang D, Barak B, Zeng M, Li C, Lu C, Wells M, Amaya A, Nguyen S, Lewis M, Sanjana N, Zhou Y, Zhang M, Zhang F, Fu Z, Feng G. Zhou Y, et al. Neuron. 2016 Jan 6;89(1):147-62. doi: 10.1016/j.neuron.2015.11.023. Epub 2015 Dec 10. Neuron. 2016. PMID: 26687841 Free PMC article.
Genome editing using Cas9 nickases.
Trevino AE, Zhang F. Trevino AE, et al. Methods Enzymol. 2014;546:161-74. doi: 10.1016/B978-0-12-801185-0.00008-8. Methods Enzymol. 2014. PMID: 25398340
Common genetic variants modulate pathogen-sensing responses in human dendritic cells.
Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, Hafler DA, Kellis M, Raychaudhuri S, Zhang F, Stranger BE, Benoist CO, De Jager PL, Regev A, Hacohen N. Lee MN, et al. Science. 2014 Mar 7;343(6175):1246980. doi: 10.1126/science.1246980. Science. 2014. PMID: 24604203 Free PMC article.
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