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13 results
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Biochemical and therapeutic effects of Omega-3 fatty acids in sickle cell disease.
Daak AA, Lopez-Toledano MA, Heeney MM. Daak AA, et al. Complement Ther Med. 2020 Aug;52:102482. doi: 10.1016/j.ctim.2020.102482. Epub 2020 Jun 9. Complement Ther Med. 2020. PMID: 32951732 Review.
Advanced Lipid Technologies® (ALT®): A Proven Formulation Platform to Enhance the Bioavailability of Lipophilic Compounds.
Lopez-Toledano MA, Saxena V, Legassie JD, Liu H, Ghanta A, Riseman S, Cocilova C, Daak A, Thorsteinsson T, Rabinowicz AL, Sancilio FD. Lopez-Toledano MA, et al. J Drug Deliv. 2019 Jul 8;2019:1957360. doi: 10.1155/2019/1957360. eCollection 2019. J Drug Deliv. 2019. PMID: 31360551 Free PMC article. Review.
SC411 treatment can enhance survival in a mouse model of sickle cell disease.
Wu CYC, Lopez-Toledano MA, Daak AA, Clemons GA, Citadin CT, Sancilio FD, Rabinowicz AL, Minagar A, Neumann JT, Lee RHC, Lin HW. Wu CYC, et al. Among authors: daak aa. Prostaglandins Leukot Essent Fatty Acids. 2020 Jul;158:102110. doi: 10.1016/j.plefa.2020.102110. Epub 2020 May 3. Prostaglandins Leukot Essent Fatty Acids. 2020. PMID: 32447175 Free article.
The differential effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on seizure frequency in patients with drug-resistant epilepsy - A randomized, double-blind, placebo-controlled trial.
Ibrahim FAS, Ghebremeskel K, Abdel-Rahman ME, Ahmed AAM, Mohmed IM, Osman G, Elseed M, Hamed A, Rabinowicz AL, Salih MAM, Elbashir MI, Daak AA. Ibrahim FAS, et al. Among authors: daak aa. Epilepsy Behav. 2018 Oct;87:32-38. doi: 10.1016/j.yebeh.2018.08.016. Epub 2018 Aug 28. Epilepsy Behav. 2018. PMID: 30170260 Clinical Trial.
Double-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial).
Daak AA, Dampier CD, Fuh B, Kanter J, Alvarez OA, Black LV, McNaull MA, Callaghan MU, George A, Neumayr L, Hilliard LM, Sancilio F, Rabinowicz AL, Heeney MM. Daak AA, et al. Blood Adv. 2018 Aug 14;2(15):1969-1979. doi: 10.1182/bloodadvances.2018021444. Blood Adv. 2018. PMID: 30097463 Free PMC article. Clinical Trial.
Coagulation profile of Sudanese children with homozygous sickle cell disease and the effect of treatment with omega-3 fatty acid on the coagulation parameters.
Awoda S, Daak AA, Husain NE, Ghebremeskel K, Elbashir MI. Awoda S, et al. Among authors: daak aa. BMC Hematol. 2017 Nov 9;17:18. doi: 10.1186/s12878-017-0089-5. eCollection 2017. BMC Hematol. 2017. PMID: 29152307 Free PMC article.
Minimal food effect for eicosapentaenoic acid and docosahexaenoic acid bioavailability from omega-3-acid ethyl esters with an Advanced Lipid TechnologiesTM (ALT®)-based formulation.
Lopez-Toledano MA, Thorsteinsson T, Daak AA, Maki KC, Johns C, Rabinowicz AL, Sancilio FD. Lopez-Toledano MA, et al. Among authors: daak aa. J Clin Lipidol. 2017 Mar-Apr;11(2):394-405. doi: 10.1016/j.jacl.2017.01.017. Epub 2017 Feb 9. J Clin Lipidol. 2017. PMID: 28502496 Clinical Trial.
Sickle cell disease in western Sudan: genetic epidemiology and predictors of knowledge attitude and practices.
Daak AA, Elsamani E, Ali EH, Mohamed FA, Abdel-Rahman ME, Elderdery AY, Talbot O, Kraft P, Ghebremeskel K, Elbashir MI, Fawzi W. Daak AA, et al. Trop Med Int Health. 2016 May;21(5):642-53. doi: 10.1111/tmi.12689. Epub 2016 Mar 29. Trop Med Int Health. 2016. PMID: 27028397 Free article.
Omega 3 (n-3) fatty acids down-regulate nuclear factor-kappa B (NF-κB) gene and blood cell adhesion molecule expression in patients with homozygous sickle cell disease.
Daak AA, Elderdery AY, Elbashir LM, Mariniello K, Mills J, Scarlett G, Elbashir MI, Ghebremeskel K. Daak AA, et al. Blood Cells Mol Dis. 2015 Jun;55(1):48-55. doi: 10.1016/j.bcmd.2015.03.014. Epub 2015 Mar 31. Blood Cells Mol Dis. 2015. PMID: 25976467 Clinical Trial.
Docosahexaenoic and eicosapentaenoic acid supplementation does not exacerbate oxidative stress or intravascular haemolysis in homozygous sickle cell patients.
Daak AA, Ghebremeskel K, Mariniello K, Attallah B, Clough P, Elbashir MI. Daak AA, et al. Prostaglandins Leukot Essent Fatty Acids. 2013 Oct;89(5):305-11. doi: 10.1016/j.plefa.2013.09.006. Epub 2013 Sep 18. Prostaglandins Leukot Essent Fatty Acids. 2013. PMID: 24095588 Clinical Trial.
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