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Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.
Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK. Friedline RH, et al. Among authors: dagdeviren s. FASEB J. 2016 Mar;30(3):1328-38. doi: 10.1096/fj.15-280610. Epub 2015 Dec 7. FASEB J. 2016. PMID: 26644351 Free PMC article.
Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance.
Dagdeviren S, Jung DY, Lee E, Friedline RH, Noh HL, Kim JH, Patel PR, Tsitsilianos N, Tsitsilianos AV, Tran DA, Tsougranis GH, Kearns CC, Uong CP, Kwon JY, Muller W, Lee KW, Kim JK. Dagdeviren S, et al. Mol Cell Biol. 2016 Nov 14;36(23):2956-2966. doi: 10.1128/MCB.00181-16. Print 2016 Dec 1. Mol Cell Biol. 2016. PMID: 27644327 Free PMC article.
IL-10 prevents aging-associated inflammation and insulin resistance in skeletal muscle.
Dagdeviren S, Jung DY, Friedline RH, Noh HL, Kim JH, Patel PR, Tsitsilianos N, Inashima K, Tran DA, Hu X, Loubato MM, Craige SM, Kwon JY, Lee KW, Kim JK. Dagdeviren S, et al. FASEB J. 2017 Feb;31(2):701-710. doi: 10.1096/fj.201600832R. Epub 2016 Nov 3. FASEB J. 2017. PMID: 27811060 Free PMC article.
These results demonstrate the importance of skeletal muscle inflammation in aging-mediated insulin resistance, and our findings further implicate a potential therapeutic role of anti-inflammatory cytokine in the treatment of aging-mediated insulin resistance.-Dagdeviren, …
These results demonstrate the importance of skeletal muscle inflammation in aging-mediated insulin resistance, and our findings further impl …
Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans.
Ehrhardt N, Cui J, Dagdeviren S, Saengnipanthkul S, Goodridge HS, Kim JK, Lantier L, Guo X, Chen YI, Raffel LJ, Buchanan TA, Hsueh WA, Rotter JI, Goodarzi MO, Péterfy M. Ehrhardt N, et al. Among authors: dagdeviren s. Obesity (Silver Spring). 2019 Mar;27(3):434-443. doi: 10.1002/oby.22418. Obesity (Silver Spring). 2019. PMID: 30801985 Free PMC article.
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice.
Walker RG, Barrandon O, Poggioli T, Dagdeviren S, Carroll SH, Mills MJ, Mendello KR, Gomez Y, Loffredo FS, Pancoast JR, Macias-Trevino C, Marts C, LeClair KB, Noh HL, Kim T, Banks AS, Kim JK, Cohen DE, Wagers AJ, Melton DA, Lee RT. Walker RG, et al. Among authors: dagdeviren s. Sci Rep. 2020 Mar 12;10(1):4561. doi: 10.1038/s41598-020-61443-y. Sci Rep. 2020. PMID: 32165710 Free PMC article.
17 results