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Functional imaging in Parkinson's disease.
Dagher A. Dagher A. Semin Neurol. 2001;21(1):23-32. doi: 10.1055/s-2001-13116. Semin Neurol. 2001. PMID: 11346022 Review.
Hemodynamic and metabolic effects of cerebral arteriovenous malformations studied by positron emission tomography.
Tyler JL, Leblanc R, Meyer E, Dagher A, Yamamoto YL, Diksic M, Hakim A. Tyler JL, et al. Among authors: dagher a. Stroke. 1989 Jul;20(7):890-8. doi: 10.1161/01.str.20.7.890. Stroke. 1989. PMID: 2787547
Abnormal basal ganglia outflow in Parkinson's disease identified with PET. Implications for higher cortical functions.
Owen AM, Doyon J, Dagher A, Sadikot A, Evans AC. Owen AM, et al. Among authors: dagher a. Brain. 1998 May;121 ( Pt 5):949-65. doi: 10.1093/brain/121.5.949. Brain. 1998. PMID: 9619196
Regional cerebral blood flow was measured in six patients with moderate Parkinson's disease and in six age-matched control subjects while they performed easy and difficult versions of a modified Tower of London planning task and a mnemonic variant of this task that …
Regional cerebral blood flow was measured in six patients with moderate Parkinson's disease and in six age-matched control subjects while th …
Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease A 3D [(18)F]dopa-PET study.
Rakshi JS, Uema T, Ito K, Bailey DL, Morrish PK, Ashburner J, Dagher A, Jenkins IH, Friston KJ, Brooks DJ. Rakshi JS, et al. Among authors: dagher a. Brain. 1999 Sep;122 ( Pt 9):1637-50. doi: 10.1093/brain/122.9.1637. Brain. 1999. PMID: 10468504
Similiar results were found with a region of interest approach, on non-transformed data, except for the focal midbrain [(18)F]dopa K(i)(o) increase seen in early Parkinson's disease. ...This suggests, therefore, that Parkinson's disease is a monoaminergic neurodegen …
Similiar results were found with a region of interest approach, on non-transformed data, except for the focal midbrain [(18)F]dopa K( …
Globus pallidus deep brain stimulation for generalized dystonia: clinical and PET investigation.
Kumar R, Dagher A, Hutchison WD, Lang AE, Lozano AM. Kumar R, et al. Among authors: dagher a. Neurology. 1999 Sep 11;53(4):871-4. doi: 10.1212/wnl.53.4.871. Neurology. 1999. PMID: 10489059
Bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) in a patient with severe idiopathic generalized dystonia resulted in immediate improvement of all aspects of dystonia. ...
Bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) in a patient with severe idiopathic generalized dystonia result …
Pharmacokinetics of radiotracers in human plasma during positron emission tomography.
Cumming P, Yokoi F, Chen A, Deep P, Dagher A, Reutens D, Kapczinski F, Wong DF, Gjedde A. Cumming P, et al. Among authors: dagher a. Synapse. 1999 Nov;34(2):124-34. doi: 10.1002/(SICI)1098-2396(199911)34:2<124::AID-SYN5>3.0.CO;2-O. Synapse. 1999. PMID: 10502311
The net rate constant of this metabolism was three times higher in a group of subjects under treatment for epilepsy, consistent with induction of hepatic microsomal enzymes by antiepileptic drugs. [(11)C]Sch 23390, a ligand for dopamine D1 receptors, was rapidly met …
The net rate constant of this metabolism was three times higher in a group of subjects under treatment for epilepsy, consistent with …
Mapping the network for planning: a correlational PET activation study with the Tower of London task.
Dagher A, Owen AM, Boecker H, Brooks DJ. Dagher A, et al. Brain. 1999 Oct;122 ( Pt 10):1973-87. doi: 10.1093/brain/122.10.1973. Brain. 1999. PMID: 10506098
There was one rest condition, and five sets of TOL problems at different complexity levels, performed on a touch-sensitive computer monitor with the right arm. ...Activation was analysed in two ways: a category analysis comparing levels of rrCBF during rest and task …
There was one rest condition, and five sets of TOL problems at different complexity levels, performed on a touch-sensitive computer m …
Stimulation of dopa decarboxylase activity in striatum of healthy human brain secondary to NMDA receptor antagonism with a low dose of amantadine.
Deep P, Dagher A, Sadikot A, Gjedde A, Cumming P. Deep P, et al. Among authors: dagher a. Synapse. 1999 Dec 15;34(4):313-8. doi: 10.1002/(SICI)1098-2396(19991215)34:4<313::AID-SYN7>3.0.CO;2-1. Synapse. 1999. PMID: 10529725 Clinical Trial.
Data from four telencephalic regions of interest containing appreciable DDC activity were analyzed with the tissue slope-intercept plot, using cerebellar cortex as the reference tissue, to estimate a coefficient of in situ FDOPA decarboxylation (k(3)(r), min(-1)). ...For a …
Data from four telencephalic regions of interest containing appreciable DDC activity were analyzed with the tissue slope-intercept plot, usi …
Neural transplantation cannula and microinjector system: experimental and clinical experience. Technical note.
Mendez I, Hong M, Smith S, Dagher A, Desrosiers J. Mendez I, et al. Among authors: dagher a. J Neurosurg. 2000 Mar;92(3):493-9. doi: 10.3171/jns.2000.92.3.0493. J Neurosurg. 2000. PMID: 10701543
The authors present a simple, reliable, and safe system for performing neural transplantation in the human brain. The device consists of a transplantation cannula and microinjector system that has been specifically designed to reduce implantation-related trauma and …
The authors present a simple, reliable, and safe system for performing neural transplantation in the human brain. The device consists …
Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line--derived neurotrophic factor in patients with Parkinson's disease. Report of two cases and technical considerations.
Mendez I, Dagher A, Hong M, Hebb A, Gaudet P, Law A, Weerasinghe S, King D, Desrosiers J, Darvesh S, Acorn T, Robertson H. Mendez I, et al. Among authors: dagher a. J Neurosurg. 2000 May;92(5):863-9. doi: 10.3171/jns.2000.92.5.0863. J Neurosurg. 2000. PMID: 10794303
The authors have studied the ability of glial cell line-derived neurotrophic factor (GDNF) to promote survival of human fetal dopaminergic tissue after a storage period of 6 days and subsequent implantation into the human putamen. ...A mean increase of 107% in putam …
The authors have studied the ability of glial cell line-derived neurotrophic factor (GDNF) to promote survival of human fetal dopaminergic t …
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