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Targeted cancer therapy with a novel low-dose rate alpha-emitting radioimmunoconjugate.
Dahle J, Borrebaek J, Jonasdottir TJ, Hjelmerud AK, Melhus KB, Bruland ØS, Press OW, Larsen RH. Dahle J, et al. Blood. 2007 Sep 15;110(6):2049-56. doi: 10.1182/blood-2007-01-066803. Epub 2007 May 29. Blood. 2007. PMID: 17536011
Preparation of TH227-labeled radioimmunoconjugates, assessment of serum stability and antigen binding ability.
Larsen RH, Borrebaek J, Dahle J, Melhus KB, Krogh C, Valan MH, Bruland OS. Larsen RH, et al. Cancer Biother Radiopharm. 2007 Jun;22(3):431-7. doi: 10.1089/cbr.2006.321. Cancer Biother Radiopharm. 2007. PMID: 17651051
Evaluation of the binding of radiolabeled rituximab to CD20-positive lymphoma cells: an in vitro feasibility study concerning low-dose-rate radioimmunotherapy with the alpha-emitter 227Th.
Melhus KB, Larsen RH, Stokke T, Kaalhus O, Selbo PK, Dahle J. Melhus KB, et al. Cancer Biother Radiopharm. 2007 Aug;22(4):469-79. doi: 10.1089/cbr.2007.371. Cancer Biother Radiopharm. 2007. PMID: 17803441
Relative biologic effects of low-dose-rate alpha-emitting 227Th-rituximab and beta-emitting 90Y-tiuexetan-ibritumomab versus external beam X-radiation.
Dahle J, Bruland OS, Larsen RH. Dahle J, et al. Int J Radiat Oncol Biol Phys. 2008 Sep 1;72(1):186-92. doi: 10.1016/j.ijrobp.2008.05.029. Int J Radiat Oncol Biol Phys. 2008. PMID: 18722269
Assessment of long-term radiotoxicity after treatment with the low-dose-rate alpha-particle-emitting radioimmunoconjugate (227)Th-rituximab.
Dahle J, Jonasdottir TJ, Heyerdahl H, Nesland JM, Borrebaek J, Hjelmerud AK, Larsen RH. Dahle J, et al. Eur J Nucl Med Mol Imaging. 2010 Jan;37(1):93-102. doi: 10.1007/s00259-009-1197-7. Eur J Nucl Med Mol Imaging. 2010. PMID: 19593562
In vitro cytotoxicity of low-dose-rate radioimmunotherapy by the alpha-emitting radioimmunoconjugate Thorium-227-DOTA-rituximab.
Dahle J, Krogh C, Melhus KB, Borrebaek J, Larsen RH, Kvinnsland Y. Dahle J, et al. Int J Radiat Oncol Biol Phys. 2009 Nov 1;75(3):886-95. doi: 10.1016/j.ijrobp.2009.04.062. Epub 2009 Aug 11. Int J Radiat Oncol Biol Phys. 2009. PMID: 19679402
A (238)Pu irradiator for exposure of cultured cells with alpha-radiation: construction, calibration and dosimetry.
Tisnek N, Kalanxhi E, Serkland CW, Iversen J, Belyakov OV, Dahle J. Tisnek N, et al. Appl Radiat Isot. 2009 Nov;67(11):1998-2002. doi: 10.1016/j.apradiso.2009.08.003. Epub 2009 Aug 15. Appl Radiat Isot. 2009. PMID: 19716308
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