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Page 1
Single nucleotide variants in UNC13C associated with neurodevelopmental disorders affect ethanol sensitivity in Drosophila.
Müller F, Neuser S, Shrestha G, Neupane NP, Götze KJ, Brunetti-Pierri N, Terrone G, Reymond A, van Gassen KL, Brilstra E, Steindl K, Begemann A, Rauch A, Rips J, Fahham D, Barakat TS, Patat O, Mortreux J, Chau MHK, Rosenfeld JA, Mizerik E, Srivastava S, Luo X, Dahse AK, Scholz N, Das J, Roman G, Langenhan T, Abou Jamra R, Mrestani A, Ljaschenko D. Müller F, et al. Among authors: dahse ak. Biochem Biophys Rep. 2025 Nov 28;45:102375. doi: 10.1016/j.bbrep.2025.102375. eCollection 2026 Mar. Biochem Biophys Rep. 2025. PMID: 41399760 Free PMC article.
Intron retention of an adhesion GPCR generates 1TM isoforms required for 7TM-GPCR function.
Bormann A, Körner MB, Dahse AK, Gläser MS, Irmer J, Lede V, Alenfelder J, Lehmann J, Hall DCN, Thane M, Schleyer M, Kostenis E, Schöneberg T, Bigl M, Langenhan T, Ljaschenko D, Scholz N. Bormann A, et al. Among authors: dahse ak. Cell Rep. 2025 Jan 28;44(1):115078. doi: 10.1016/j.celrep.2024.115078. Epub 2024 Dec 19. Cell Rep. 2025. PMID: 39705141 Free article.
Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation.
Scholz N, Dahse AK, Kemkemer M, Bormann A, Auger GM, Vieira Contreras F, Ernst LF, Staake H, Körner MB, Buhlan M, Meyer-Mölck A, Chung YK, Blanco-Redondo B, Klose F, Jarboui MA, Ljaschenko D, Bigl M, Langenhan T. Scholz N, et al. Among authors: dahse ak. Nature. 2023 Mar;615(7954):945-953. doi: 10.1038/s41586-023-05802-5. Epub 2023 Mar 8. Nature. 2023. PMID: 36890234
Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain.
Beliu G, Altrichter S, Guixà-González R, Hemberger M, Brauer I, Dahse AK, Scholz N, Wieduwild R, Kuhlemann A, Batebi H, Seufert F, Pérez-Hernández G, Hildebrand PW, Sauer M, Langenhan T. Beliu G, et al. Among authors: dahse ak. Mol Cell. 2021 Mar 4;81(5):905-921.e5. doi: 10.1016/j.molcel.2020.12.042. Epub 2021 Jan 25. Mol Cell. 2021. PMID: 33497605 Free article.