Dai D - Search Results

1

A specific interaction of small molecule entry inhibitors with the envelope glycoprotein complex of the Junín hemorrhagic fever arenavirus.

Thomas CJ, Casquilho-Gray HE, York J, DeCamp DL, Dai D, Petrilli EB, Boger DL, Slayden RA, Amberg SM, Sprang SR, Nunberg JH. Thomas CJ, et al. Among authors: dai d. J Biol Chem. 2011 Feb 25;286(8):6192-200. doi: 10.1074/jbc.M110.196428. Epub 2010 Dec 15. J Biol Chem. 2011. PMID: 21159779 Free PMC article.

2

pH-induced activation of arenavirus membrane fusion is antagonized by small-molecule inhibitors.

York J, Dai D, Amberg SM, Nunberg JH. York J, et al. Among authors: dai d. J Virol. 2008 Nov;82(21):10932-9. doi: 10.1128/JVI.01140-08. Epub 2008 Sep 3. J Virol. 2008. PMID: 18768973 Free PMC article.

3

Identification of a broad-spectrum arenavirus entry inhibitor.

Larson RA, Dai D, Hosack VT, Tan Y, Bolken TC, Hruby DE, Amberg SM. Larson RA, et al. Among authors: dai d. J Virol. 2008 Nov;82(21):10768-75. doi: 10.1128/JVI.00941-08. Epub 2008 Aug 20. J Virol. 2008. PMID: 18715909 Free PMC article.

4

Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole.

Dai D, Burgeson JR, Gharaibeh DN, Moore AL, Larson RA, Cerruti NR, Amberg SM, Bolken TC, Hruby DE. Dai D, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):744-9. doi: 10.1016/j.bmcl.2012.11.095. Epub 2012 Dec 1. Bioorg Med Chem Lett. 2013. PMID: 23265895

5

Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole and related heterocycles.

Burgeson JR, Moore AL, Gharaibeh DN, Larson RA, Cerruti NR, Amberg SM, Hruby DE, Dai D. Burgeson JR, et al. Among authors: dai d. Bioorg Med Chem Lett. 2013 Feb 1;23(3):750-6. doi: 10.1016/j.bmcl.2012.11.093. Epub 2012 Dec 1. Bioorg Med Chem Lett. 2013. PMID: 23265900

6

Lead optimization of an acylhydrazone scaffold possessing antiviral activity against Lassa virus.

Burgeson JR, Gharaibeh DN, Moore AL, Larson RA, Amberg SM, Bolken TC, Hruby DE, Dai D. Burgeson JR, et al. Among authors: dai d. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5840-3. doi: 10.1016/j.bmcl.2013.08.103. Epub 2013 Sep 5. Bioorg Med Chem Lett. 2013. PMID: 24064500 Free PMC article.

7

A potent Lassa virus antiviral targets an arenavirus virulence determinant.

Madu IG, Files M, Gharaibeh DN, Moore AL, Jung KH, Gowen BB, Dai D, Jones KF, Tyavanagimatt SR, Burgeson JR, Korth MJ, Bedard KM, Iadonato SP, Amberg SM. Madu IG, et al. Among authors: dai d. PLoS Pathog. 2018 Dec 21;14(12):e1007439. doi: 10.1371/journal.ppat.1007439. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30576397 Free PMC article.

8

SAR analysis of a series of acylthiourea derivatives possessing broad-spectrum antiviral activity.

Burgeson JR, Moore AL, Boutilier JK, Cerruti NR, Gharaibeh DN, Lovejoy CE, Amberg SM, Hruby DE, Tyavanagimatt SR, Allen RD 3rd, Dai D. Burgeson JR, et al. Among authors: dai d. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4263-72. doi: 10.1016/j.bmcl.2012.05.035. Epub 2012 May 17. Bioorg Med Chem Lett. 2012. PMID: 22664128

9

Evaluation of Lassa antiviral compound ST-193 in a guinea pig model.

Cashman KA, Smith MA, Twenhafel NA, Larson RA, Jones KF, Allen RD 3rd, Dai D, Chinsangaram J, Bolken TC, Hruby DE, Amberg SM, Hensley LE, Guttieri MC. Cashman KA, et al. Among authors: dai d. Antiviral Res. 2011 Apr;90(1):70-9. doi: 10.1016/j.antiviral.2011.02.012. Epub 2011 Mar 1. Antiviral Res. 2011. PMID: 21371508 Free PMC article.

10

Discovery of small molecule inhibitors of ubiquitin-like poxvirus proteinase I7L using homology modeling and covalent docking approaches.

Katritch V, Byrd CM, Tseitin V, Dai D, Raush E, Totrov M, Abagyan R, Jordan R, Hruby DE. Katritch V, et al. Among authors: dai d. J Comput Aided Mol Des. 2007 Oct-Nov;21(10-11):549-58. doi: 10.1007/s10822-007-9138-7. Epub 2007 Oct 25. J Comput Aided Mol Des. 2007. PMID: 17960327 Free PMC article.

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