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Page 1
Daidzein and its Effects on Brain.
Ahmed T, Javed S, Tariq A, Budzyńska B, D'Onofrio G, Daglia M, Nabavi SF, Nabavi SM. Ahmed T, et al. Curr Med Chem. 2017;24(4):365-375. doi: 10.2174/0929867323666161101140214. Curr Med Chem. 2017. PMID: 27804870 Review.
These effects are mainly elicited through the interaction of daidzein with different signaling molecules and receptors, thereby offering neuroprotection. ...In addition, the effects of daidzein on other disorders have also been examined briefly in this article....
These effects are mainly elicited through the interaction of daidzein with different signaling molecules and receptors, thereby offer …
Daidzein, its effects on impaired glucose and lipid metabolism and vascular inflammation associated with type 2 diabetes.
Das D, Sarkar S, Bordoloi J, Wann SB, Kalita J, Manna P. Das D, et al. Biofactors. 2018 Sep;44(5):407-417. doi: 10.1002/biof.1439. Epub 2018 Sep 6. Biofactors. 2018. PMID: 30191623 Review.
Fermented soybean is the major source of daidzein; however, it can also be formed via the consumption of its glycosylated moiety, daidzin with subsequent hydrolysis by intestinal bacterial enzyme. ...The molecular mechanisms underlying the action of daidzein include …
Fermented soybean is the major source of daidzein; however, it can also be formed via the consumption of its glycosylated moiety, dai …
Daidzein ameliorates diabetic retinopathy in experimental animals.
Laddha AP, Kulkarni YA. Laddha AP, et al. Life Sci. 2021 Jan 15;265:118779. doi: 10.1016/j.lfs.2020.118779. Epub 2020 Nov 17. Life Sci. 2021. PMID: 33217441
Oxidative stress was also found to be significantly reduced after 28 days of daidzein treatment. Histopathological findings showed a reduction in retinal thickness after daidzein treatment. ...Thus, Daidzein can be considered as an effective treatment option …
Oxidative stress was also found to be significantly reduced after 28 days of daidzein treatment. Histopathological findings showed a …
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
Shu J, Hu L, Wu Y, Chen L, Huang K, Wang Z, Liang M. Shu J, et al. Eur J Pharmacol. 2022 Mar 15;919:174805. doi: 10.1016/j.ejphar.2022.174805. Epub 2022 Feb 10. Eur J Pharmacol. 2022. PMID: 35151651
This study aimed to reveal its role in myocardial fibrosis. Our results indicate that daidzein had a nontoxic effect on cardiac fibroblasts and that TGF-beta1 and TGFbetaRI levels were gradually decreased by daidzein in a dose-dependent manner. ...Additionally, d …
This study aimed to reveal its role in myocardial fibrosis. Our results indicate that daidzein had a nontoxic effect on cardiac fibro …
Daidzein mitigates myocardial injury in streptozotocin-induced diabetes in rats.
Laddha AP, Kulkarni YA. Laddha AP, et al. Life Sci. 2021 Nov 1;284:119664. doi: 10.1016/j.lfs.2021.119664. Epub 2021 Jun 6. Life Sci. 2021. PMID: 34090859
Animals received daidzein at a dose of 25, 50, and 100 mg/kg orally for the next four weeks. ...Treatment with daidzein at dose 100 mg/kg significantly improved the SBP, DBP, and MAP. ...
Animals received daidzein at a dose of 25, 50, and 100 mg/kg orally for the next four weeks. ...Treatment with daidzein at dos …
The 6-month effect of whole soy and purified isoflavones daidzein on thyroid function-A double-blind, randomized, placebo controlled trial among Chinese equol-producing postmenopausal women.
Liu ZM, Zhang D, Li G, Ho SC, Chen YM, Ma J, Huang Q, Li S, Ling WH. Liu ZM, et al. Phytother Res. 2021 Oct;35(10):5838-5846. doi: 10.1002/ptr.7244. Epub 2021 Sep 7. Phytother Res. 2021. PMID: 34494323 Clinical Trial.
The aim of this study was to examine the effect of whole soy and purified daidzein on markers of thyroid function in Chinese postmenopausal women who were equol-producers. Total 270 eligible women were randomized to either one of the three isocaloric supplements: 40 g soy …
The aim of this study was to examine the effect of whole soy and purified daidzein on markers of thyroid function in Chinese postmeno …
Daidzein promotes milk synthesis and proliferation of mammary epithelial cells via the estrogen receptor α-dependent NFκB1 activation.
Yu M, Qi H, Gao X. Yu M, et al. Anim Biotechnol. 2022 Feb;33(1):43-52. doi: 10.1080/10495398.2020.1763376. Epub 2020 May 13. Anim Biotechnol. 2022. PMID: 32401613
Daidzein also stimulated mTOR activation and Cyclin D1 and SREBP-1c expression. Daidzein induced the expression and nuclear localization of estrogen receptor alpha (ERalpha), and ERalpha knockdown blocked the stimulation of daidzein on these above signaling p …
Daidzein also stimulated mTOR activation and Cyclin D1 and SREBP-1c expression. Daidzein induced the expression and nuclear lo …
Daidzein Activates Akt Pathway to Promote the Proliferation of Female Germline Stem Cells through Upregulating Clec11a.
Li F, Hu X, Wu J. Li F, et al. Stem Cell Rev Rep. 2022 Dec;18(8):3021-3032. doi: 10.1007/s12015-022-10394-0. Epub 2022 Jun 3. Stem Cell Rev Rep. 2022. PMID: 35655001
However, knockdown of Clec11a inhibited the viability and proliferation of FGSCs, which could not be rescued by the administration of daidzein. These results indicate that daidzein promoted the viability and proliferation of FGSCs through Clec11a. In addition, both …
However, knockdown of Clec11a inhibited the viability and proliferation of FGSCs, which could not be rescued by the administration of dai …
Daidzein ameliorates experimental acute reflux esophagitis in rats via regulation of cytokines.
Deng T, Zhang N, Liu Y, Li J. Deng T, et al. Pharmazie. 2021 Feb 25;76(2):84-91. doi: 10.1691/ph.2021.01003. Pharmazie. 2021. PMID: 33714284
Context: Daidzein is a secondary metabolite derived from plants, has a flavonoid structure and is known for its protective activity in gastrointestinal disorders. ...Methods: Adult male Wistar rats were classified into six groups: normal control, ER + different doses of …
Context: Daidzein is a secondary metabolite derived from plants, has a flavonoid structure and is known for its protective activity i …
Daidzein stimulates fatty acid-induced fat deposition in C2C12 myoblast cells via the G protein-coupled receptor 30 pathway.
Zhou C, Li P, Han M, Gao X. Zhou C, et al. Anim Biotechnol. 2022 Oct;33(5):851-863. doi: 10.1080/10495398.2020.1842749. Epub 2020 Nov 8. Anim Biotechnol. 2022. PMID: 33164657
In the presence of FAs, daidzein enhanced FAs-induced fat deposition and the SREBP-1c signaling. ...Daidzein did not affect ERalpha expression in cells, but it stimulated GPR30 expression and cytoplasmic localization. ...
In the presence of FAs, daidzein enhanced FAs-induced fat deposition and the SREBP-1c signaling. ...Daidzein did not affect ER …
4,157 results