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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1970 1
1971 1
1972 2
1975 2
1976 1
1977 3
1978 1
1979 4
1980 5
1983 2
1984 7
1985 3
1986 3
1987 5
1988 8
1989 3
1990 4
1991 13
1992 9
1993 19
1994 25
1995 40
1996 49
1997 57
1998 108
1999 99
2000 105
2001 96
2002 142
2003 159
2004 174
2005 179
2006 196
2007 211
2008 195
2009 195
2010 209
2011 183
2012 196
2013 183
2014 189
2015 186
2016 163
2017 165
2018 164
2019 193
2020 205
2021 198
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3,926 results
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Page 1
Daidzein and its Effects on Brain.
Ahmed T, Javed S, Tariq A, Budzyńska B, D'Onofrio G, Daglia M, Nabavi SF, Nabavi SM. Ahmed T, et al. Curr Med Chem. 2017;24(4):365-375. doi: 10.2174/0929867323666161101140214. Curr Med Chem. 2017. PMID: 27804870 Review.
These effects are mainly elicited through the interaction of daidzein with different signaling molecules and receptors, thereby offering neuroprotection. ...In addition, the effects of daidzein on other disorders have also been examined briefly in this article....
These effects are mainly elicited through the interaction of daidzein with different signaling molecules and receptors, thereby offer …
Daidzein, its effects on impaired glucose and lipid metabolism and vascular inflammation associated with type 2 diabetes.
Das D, Sarkar S, Bordoloi J, Wann SB, Kalita J, Manna P. Das D, et al. Biofactors. 2018 Sep;44(5):407-417. doi: 10.1002/biof.1439. Epub 2018 Sep 6. Biofactors. 2018. PMID: 30191623 Review.
Fermented soybean is the major source of daidzein; however, it can also be formed via the consumption of its glycosylated moiety, daidzin with subsequent hydrolysis by intestinal bacterial enzyme. ...The molecular mechanisms underlying the action of daidzein include …
Fermented soybean is the major source of daidzein; however, it can also be formed via the consumption of its glycosylated moiety, dai …
Daidzein ameliorates LPS-induced hepatocyte injury by inhibiting inflammation and oxidative stress.
Yu Z, Yang L, Deng S, Liang M. Yu Z, et al. Eur J Pharmacol. 2020 Oct 15;885:173399. doi: 10.1016/j.ejphar.2020.173399. Epub 2020 Jul 24. Eur J Pharmacol. 2020. PMID: 32712091
However, little is known about whether daidzein could attenuate lipopolysaccharide (LPS)-induced ALI. We investigated the effects of daidzein on hepatocyte injury and its underlying mechanisms. ...Western blot analysis showed that daidzein inhibited LPS-induc …
However, little is known about whether daidzein could attenuate lipopolysaccharide (LPS)-induced ALI. We investigated the effects of …
Daidzein ameliorates diabetic retinopathy in experimental animals.
Laddha AP, Kulkarni YA. Laddha AP, et al. Life Sci. 2021 Jan 15;265:118779. doi: 10.1016/j.lfs.2020.118779. Epub 2020 Nov 17. Life Sci. 2021. PMID: 33217441
Oxidative stress was also found to be significantly reduced after 28 days of daidzein treatment. Histopathological findings showed a reduction in retinal thickness after daidzein treatment. ...Thus, Daidzein can be considered as an effective treatment option …
Oxidative stress was also found to be significantly reduced after 28 days of daidzein treatment. Histopathological findings showed a …
Dietary daidzein decreases food intake accompanied with delayed gastric emptying in ovariectomized rats.
Adhikari S, Bhattarai K, Abe Y, Kira M, Fujitani M, Miyada T, Kishida T. Adhikari S, et al. Biosci Biotechnol Biochem. 2020 Jun;84(6):1232-1238. doi: 10.1080/09168451.2020.1723404. Epub 2020 Feb 18. Biosci Biotechnol Biochem. 2020. PMID: 32067573
We previously found that equol, a metabolite of intestinal bacterial conversion from soy isoflavone daidzein, has female-specific anorectic effects. In the present study, we used seven-week-old female ovariectomized (OVX) Sprague Dawley rats to test the hypothesis that the …
We previously found that equol, a metabolite of intestinal bacterial conversion from soy isoflavone daidzein, has female-specific ano …
Daidzein promotes the expression of oxidative phosphorylation- and fatty acid oxidation-related genes via an estrogen-related receptor alpha pathway to decrease lipid accumulation in muscle cells.
Kitamura K, Erlangga JS, Tsukamoto S, Sakamoto Y, Mabashi-Asazuma H, Iida K. Kitamura K, et al. J Nutr Biochem. 2020 Mar;77:108315. doi: 10.1016/j.jnutbio.2019.108315. Epub 2019 Dec 16. J Nutr Biochem. 2020. PMID: 31923756
Using a reporter assay, we showed that daidzein enhanced the promoter activity of these genes and that ERRalpha responsive elements in the promoter region were necessary for the action of daidzein. Finally, daidzein significantly decreased lipid accumulation …
Using a reporter assay, we showed that daidzein enhanced the promoter activity of these genes and that ERRalpha responsive elements i …
Dietary Daidzein Supplementation During Pregnancy Facilitates Fetal Growth in Rats.
Zhang Q, Xie H, Chen D, Yu B, Huang Z, Zheng P, Mao X, Yu J, Luo Y, Luo J, He J. Zhang Q, et al. Mol Nutr Food Res. 2018 Dec;62(24):e1800921. doi: 10.1002/mnfr.201800921. Epub 2018 Nov 9. Mol Nutr Food Res. 2018. PMID: 30365232
SCOPE: Daidzein, a natural isoflavone with estrogen-like activity, has been implicated in the regulation of reproductive performance in mammals. ...CONCLUSION: These results not only indicate a beneficial effect of daidzein supplementation on reproductive performanc …
SCOPE: Daidzein, a natural isoflavone with estrogen-like activity, has been implicated in the regulation of reproductive performance …
Rhizosphere modelling reveals spatiotemporal distribution of daidzein shaping soybean rhizosphere bacterial community.
Okutani F, Hamamoto S, Aoki Y, Nakayasu M, Nihei N, Nishimura T, Yazaki K, Sugiyama A. Okutani F, et al. Plant Cell Environ. 2020 Apr;43(4):1036-1046. doi: 10.1111/pce.13708. Epub 2020 Jan 2. Plant Cell Environ. 2020. PMID: 31875335
We then analysed how daidzein affects bacterial communities using soils artificially treated with daidzein. ...After 14 days in a rhizobox, daidzein was only present within 2 mm of root surfaces. Soils with different concentrations of daidzein showed d …
We then analysed how daidzein affects bacterial communities using soils artificially treated with daidzein. ...After 14 days i …
Development of daidzein nanosuspensions: Preparation, characterization, in vitro evaluation, and pharmacokinetic analysis.
Wang H, Xiao Y, Wang H, Sang Z, Han X, Ren S, Du R, Shi X, Xie Y. Wang H, et al. Int J Pharm. 2019 Jul 20;566:67-76. doi: 10.1016/j.ijpharm.2019.05.051. Epub 2019 May 21. Int J Pharm. 2019. PMID: 31125715
Due to the increased solubility and dissolution rate, the oral bioavailability of daidzein NS in rats was 1.63-2.19 times greater than that of crude daidzein. In particular, among the investigated seven daidzein NS formulations, daidzein NS prepared wi …
Due to the increased solubility and dissolution rate, the oral bioavailability of daidzein NS in rats was 1.63-2.19 times greater tha …
Synergetic inhibition of daidzein and regular exercise on breast cancer in bearing-4T1 mice by regulating NK cells and apoptosis pathway.
Wang B, Xu H, Hu X, Ma W, Zhang J, Li Y, Yu M, Zhang Y, Li X, Ye X. Wang B, et al. Life Sci. 2020 Mar 15;245:117387. doi: 10.1016/j.lfs.2020.117387. Epub 2020 Jan 30. Life Sci. 2020. PMID: 32007575
BALB/c mice pretreated with regular exercise training for 20 days (15 m/min, 60 min/d) were orthotopically transplanted with mouse breast cancer cells (4T1), and then treated with daidzein (145 mg/kg) by gavage for another 22 days. Results showed that exercise or daidze
BALB/c mice pretreated with regular exercise training for 20 days (15 m/min, 60 min/d) were orthotopically transplanted with mouse breast ca …
3,926 results