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Drug development from marine natural products.

Molinski TF, Dalisay DS, Lievens SL, Saludes JP. Molinski TF, et al. Among authors: dalisay ds. Nat Rev Drug Discov. 2009 Jan;8(1):69-85. doi: 10.1038/nrd2487. Epub 2008 Dec 19. Nat Rev Drug Discov. 2009. PMID: 19096380 Review.

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Oceanalin B, a Hybrid α,ω-Bifunctionalized Sphingoid Tetrahydroisoquinoline β-Glycoside from the Marine Sponge Oceanapia sp.

Makarieva TN, Ivanchina NV, Dmitrenok PS, Guzii AG, Stonik VA, Dalisay DS, Molinski TF. Makarieva TN, et al. Among authors: dalisay ds. Mar Drugs. 2021 Nov 12;19(11):635. doi: 10.3390/md19110635. Mar Drugs. 2021. PMID: 34822506 Free PMC article.

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Multimeric TAT peptides are effective in vitro inhibitors of Staphylococcus saprophyticus.

Chiongson JBV, Sabido EM, Lin KG, Alea GV, Dalisay DS, Wu SH, Saludes JP. Chiongson JBV, et al. Among authors: dalisay ds. Chem Biol Drug Des. 2020 Dec;96(6):1348-1354. doi: 10.1111/cbdd.13706. Epub 2020 Jun 20. Chem Biol Drug Des. 2020. PMID: 32562357

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Oceanapiside, a Marine Natural Product, Targets the Sphingolipid Pathway of Fluconazole-Resistant Candida glabrata.

Dalisay DS, Rogers EW, Molinski TF. Dalisay DS, et al. Mar Drugs. 2021 Feb 26;19(3):126. doi: 10.3390/md19030126. Mar Drugs. 2021. PMID: 33652774 Free PMC article.

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Multiple strain analysis of Streptomyces species from Philippine marine sediments reveals intraspecies heterogeneity in antibiotic activities.

Tenebro CP, Trono DJVL, Vicera CVB, Sabido EM, Ysulat JA Jr, Macaspac AJM, Tampus KA, Fabrigar TAP, Saludes JP, Dalisay DS. Tenebro CP, et al. Among authors: dalisay ds. Sci Rep. 2021 Sep 2;11(1):17544. doi: 10.1038/s41598-021-96886-4. Sci Rep. 2021. PMID: 34475427 Free PMC article.

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Publisher Correction: Multiple strain analysis of Streptomyces species from Philippine marine sediments reveals intraspecies heterogeneity in antibiotic activities.

Tenebro CP, Trono DJVL, Vicera CVB, Sabido EM, Ysulat JA Jr, Macaspac AJM, Tampus KA, Fabrigar TAP, Saludes JP, Dalisay DS. Tenebro CP, et al. Among authors: dalisay ds. Sci Rep. 2021 Sep 20;11(1):19046. doi: 10.1038/s41598-021-98601-9. Sci Rep. 2021. PMID: 34545142 Free PMC article. No abstract available.

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N-carbamoylation of 2,4-diaminobutyrate reroutes the outcome in padanamide biosynthesis.

Du YL, Dalisay DS, Andersen RJ, Ryan KS. Du YL, et al. Among authors: dalisay ds. Chem Biol. 2013 Aug 22;20(8):1002-11. doi: 10.1016/j.chembiol.2013.06.013. Epub 2013 Aug 1. Chem Biol. 2013. PMID: 23911586

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Insights into the Variation in Bioactivities of Closely Related Streptomyces Strains from Marine Sediments of the Visayan Sea against ESKAPE and Ovarian Cancer.

Sabido EM, Tenebro CP, Trono DJVL, Vicera CVB, Leonida SFL, Maybay JJWB, Reyes-Salarda R, Amago DS, Aguadera AMV, Octaviano MC, Saludes JP, Dalisay DS. Sabido EM, et al. Among authors: dalisay ds. Mar Drugs. 2021 Jul 31;19(8):441. doi: 10.3390/md19080441. Mar Drugs. 2021. PMID: 34436280 Free PMC article.

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The Isorhamnetin-Containing Fraction of Philippine Honey Produced by the Stingless Bee Tetragonula biroi Is an Antibiotic against Multidrug-Resistant Staphylococcus aureus.

Suarez AFL, Tirador ADG, Villorente ZM, Bagarinao CF, Sollesta JVN, Dumancas GG, Sun Z, Zhan ZQ, Saludes JP, Dalisay DS. Suarez AFL, et al. Among authors: dalisay ds. Molecules. 2021 Mar 17;26(6):1688. doi: 10.3390/molecules26061688. Molecules. 2021. PMID: 33802916 Free PMC article.

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Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans.

Dalisay DS, Saludes JP, Molinski TF. Dalisay DS, et al. Bioorg Med Chem. 2011 Nov 15;19(22):6654-7. doi: 10.1016/j.bmc.2011.05.041. Epub 2011 May 27. Bioorg Med Chem. 2011. PMID: 21715177 Free PMC article.

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