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Acetylation inactivates the transcriptional repressor BCL6.
Bereshchenko OR, Gu W, Dalla-Favera R. Bereshchenko OR, et al. Nat Genet. 2002 Dec;32(4):606-13. doi: 10.1038/ng1018. Epub 2002 Oct 28. Nat Genet. 2002. PMID: 12402037
BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci.
Pasqualucci L, Migliazza A, Fracchiolla N, William C, Neri A, Baldini L, Chaganti RS, Klein U, K├╝ppers R, Rajewsky K, Dalla-Favera R. Pasqualucci L, et al. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11816-21. doi: 10.1073/pnas.95.20.11816. Proc Natl Acad Sci U S A. 1998. PMID: 9751748 Free PMC article.
BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor.
Chang CC, Ye BH, Chaganti RS, Dalla-Favera R. Chang CC, et al. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):6947-52. doi: 10.1073/pnas.93.14.6947. Proc Natl Acad Sci U S A. 1996. PMID: 8692924 Free PMC article.
Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.
Zhang J, Dominguez-Sola D, Hussein S, Lee JE, Holmes AB, Bansal M, Vlasevska S, Mo T, Tang H, Basso K, Ge K, Dalla-Favera R, Pasqualucci L. Zhang J, et al. Nat Med. 2015 Oct;21(10):1190-8. doi: 10.1038/nm.3940. Epub 2015 Sep 14. Nat Med. 2015. PMID: 26366712 Free PMC article.
Transcriptional analysis of the B cell germinal center reaction.
Klein U, Tu Y, Stolovitzky GA, Keller JL, Haddad J Jr, Miljkovic V, Cattoretti G, Califano A, Dalla-Favera R. Klein U, et al. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2639-44. doi: 10.1073/pnas.0437996100. Epub 2003 Feb 25. Proc Natl Acad Sci U S A. 2003. PMID: 12604779 Free PMC article.
RNAs with multiple personalities.
Maute RL, Dalla-Favera R, Basso K. Maute RL, et al. Wiley Interdiscip Rev RNA. 2014 Jan-Feb;5(1):1-13. doi: 10.1002/wrna.1193. Epub 2013 Aug 20. Wiley Interdiscip Rev RNA. 2014. PMID: 24039180 Review.
A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.
Lefebvre C, Rajbhandari P, Alvarez MJ, Bandaru P, Lim WK, Sato M, Wang K, Sumazin P, Kustagi M, Bisikirska BC, Basso K, Beltrao P, Krogan N, Gautier J, Dalla-Favera R, Califano A. Lefebvre C, et al. Mol Syst Biol. 2010 Jun 8;6:377. doi: 10.1038/msb.2010.31. Mol Syst Biol. 2010. PMID: 20531406 Free PMC article.
Genome-wide identification of post-translational modulators of transcription factor activity in human B cells.
Wang K, Saito M, Bisikirska BC, Alvarez MJ, Lim WK, Rajbhandari P, Shen Q, Nemenman I, Basso K, Margolin AA, Klein U, Dalla-Favera R, Califano A. Wang K, et al. Nat Biotechnol. 2009 Sep;27(9):829-39. doi: 10.1038/nbt.1563. Epub 2009 Sep 9. Nat Biotechnol. 2009. PMID: 19741643 Free PMC article.
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