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Lysosomal NKG7 restrains mTORC1 activity to promote CD8+ T cell durability and tumor control.
Ham H, Hirdler JB, Bihnam DT, Mao Z, Gicobi JK, Macedo BG, Rodriguez-Quevedo MF, Schultz DF, Correia C, Zhong J, Martinez KE, Banuelos A, Ashton DS, Lagnado AB, Guo R, Pessoa R, Pandey A, Li H, Lucien F, Borges da Silva H, Dong H, Billadeau DD. Ham H, et al. Among authors: ashton ds. Nat Commun. 2025 Feb 14;16(1):1628. doi: 10.1038/s41467-025-56931-6. Nat Commun. 2025. PMID: 39952956 Free PMC article.
A Dual Role for NKG7 in T-cell Cytotoxicity and Longevity.
Dong H, Ham H, Barham W, Wen T, Hirdler JB, Mao Z, Ashton DS, Zhang W, Lucien-Matteoni F, Borges da Silva H, Billadeau DD. Dong H, et al. Among authors: ashton ds. Cancer Immunol Res. 2025 Oct 1;13(10):1510-1515. doi: 10.1158/2326-6066.CIR-25-0384. Cancer Immunol Res. 2025. PMID: 40824199 Free PMC article. Review.
Influence of PEGylation on the Strength of Protein Surface Salt Bridges.
Xiao Q, Draper SRE, Smith MS, Brown N, Pugmire NAB, Ashton DS, Carter AJ, Lawrence EEK, Price JL. Xiao Q, et al. Among authors: ashton ds. ACS Chem Biol. 2019 Jul 19;14(7):1652-1659. doi: 10.1021/acschembio.9b00432. Epub 2019 Jun 24. ACS Chem Biol. 2019. PMID: 31188563 Free PMC article.