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Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination.
Lai F, Damle SS, Ling KK, Rigo F. Lai F, et al. Among authors: damle ss. Mol Cell. 2020 Mar 5;77(5):1032-1043.e4. doi: 10.1016/j.molcel.2019.12.029. Epub 2020 Jan 7. Mol Cell. 2020. PMID: 31924447
2'-O-methoxyethyl splice-switching oligos correct splicing from IVS2-745 β-thalassemia patient cells restoring HbA production and chain rebalance.
Dong A, Ghiaccio V, Motta I, Guo S, Peralta R, Freier SM, Watt A, Damle S, Ikawa Y, Jarocha D, Chappell M, Stephanou C, Delbini P, Chen C, Christou S, Kleanthous M, Smith-Whitley K, Manwani D, Casu C, Abdulmalik O, Cappellini MD, Rivella S, Breda L. Dong A, et al. Haematologica. 2020 May 21:haematol.2019.226852. doi: 10.3324/haematol.2019.226852. Online ahead of print. Haematologica. 2020. PMID: 32439726
Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-induced Goblet Cell Metaplasia in the Adult Murine Lung.
Carrer M, Crosby JR, Sun G, Zhao C, Damle SS, Kuntz SG, Monia BP, Hart CE, Grossman TR. Carrer M, et al. Among authors: damle ss. Am J Respir Cell Mol Biol. 2020 Jul;63(1):46-56. doi: 10.1165/rcmb.2019-0257OC. Am J Respir Cell Mol Biol. 2020. PMID: 32176858
A modular analysis of microglia gene expression, insights into the aged phenotype.
Cho CE, Damle SS, Wancewicz EV, Mukhopadhyay S, Hart CE, Mazur C, Swayze EE, Kamme F. Cho CE, et al. Among authors: damle ss. BMC Genomics. 2019 Feb 28;20(1):164. doi: 10.1186/s12864-019-5549-9. BMC Genomics. 2019. PMID: 30819113 Free PMC article.
Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations.
Huang L, Low A, Damle SS, Keenan MM, Kuntz S, Murray SF, Monia BP, Guo S. Huang L, et al. Among authors: damle ss. Genome Biol. 2018 Jan 15;19(1):4. doi: 10.1186/s13059-017-1386-9. Genome Biol. 2018. PMID: 29334995 Free PMC article.
Antisense oligonucleotides targeting translation inhibitory elements in 5' UTRs can selectively increase protein levels.
Liang XH, Sun H, Shen W, Wang S, Yao J, Migawa MT, Bui HH, Damle SS, Riney S, Graham MJ, Crooke RM, Crooke ST. Liang XH, et al. Among authors: damle ss. Nucleic Acids Res. 2017 Sep 19;45(16):9528-9546. doi: 10.1093/nar/gkx632. Nucleic Acids Res. 2017. PMID: 28934489 Free PMC article.
Noble metal-free bifunctional oxygen evolution and oxygen reduction acidic media electro-catalysts.
Patel PP, Datta MK, Velikokhatnyi OI, Kuruba R, Damodaran K, Jampani P, Gattu B, Shanthi PM, Damle SS, Kumta PN. Patel PP, et al. Among authors: damle ss. Sci Rep. 2016 Jul 6;6:28367. doi: 10.1038/srep28367. Sci Rep. 2016. PMID: 27380719 Free PMC article.
Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment.
Kueh HY, Yui MA, Ng KK, Pease SS, Zhang JA, Damle SS, Freedman G, Siu S, Bernstein ID, Elowitz MB, Rothenberg EV. Kueh HY, et al. Among authors: damle ss. Nat Immunol. 2016 Aug;17(8):956-65. doi: 10.1038/ni.3514. Epub 2016 Jul 4. Nat Immunol. 2016. PMID: 27376470 Free PMC article.
Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function.
Lima WF, Murray HM, Damle SS, Hart CE, Hung G, De Hoyos CL, Liang XH, Crooke ST. Lima WF, et al. Among authors: damle ss. Nucleic Acids Res. 2016 Jun 20;44(11):5299-312. doi: 10.1093/nar/gkw350. Epub 2016 Apr 29. Nucleic Acids Res. 2016. PMID: 27131367 Free PMC article.
Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration.
Huang L, Damle SS, Booten S, Singh P, Sabripour M, Hsu J, Jo M, Katz M, Watt A, Hart CE, Freier SM, Monia BP, Guo S. Huang L, et al. Among authors: damle ss. PLoS One. 2015 Jul 24;10(7):e0132798. doi: 10.1371/journal.pone.0132798. eCollection 2015. PLoS One. 2015. PMID: 26207833 Free PMC article.
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