Damm G - Search Results

1

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression.

Lucarelli P, Schilling M, Kreutz C, Vlasov A, Boehm ME, Iwamoto N, Steiert B, Lattermann S, Wäsch M, Stepath M, Matter MS, Heikenwälder M, Hoffmann K, Deharde D, Damm G, Seehofer D, Muciek M, Gretz N, Lehmann WD, Timmer J, Klingmüller U. Lucarelli P, et al. Among authors: damm g. Cell Syst. 2018 Jan 24;6(1):75-89.e11. doi: 10.1016/j.cels.2017.11.010. Epub 2017 Dec 13. Cell Syst. 2018. PMID: 29248373 Free article.

2

Featured Article: Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells.

Pfeiffer E, Kegel V, Zeilinger K, Hengstler JG, Nüssler AK, Seehofer D, Damm G. Pfeiffer E, et al. Among authors: damm g. Exp Biol Med (Maywood). 2015 May;240(5):645-56. doi: 10.1177/1535370214558025. Epub 2014 Nov 12. Exp Biol Med (Maywood). 2015. PMID: 25394621 Free PMC article.

3

A systematic comparison of the impact of inflammatory signaling on absorption, distribution, metabolism, and excretion gene expression and activity in primary human hepatocytes and HepaRG cells.

Klein M, Thomas M, Hofmann U, Seehofer D, Damm G, Zanger UM. Klein M, et al. Among authors: damm g. Drug Metab Dispos. 2015 Feb;43(2):273-83. doi: 10.1124/dmd.114.060962. Epub 2014 Dec 5. Drug Metab Dispos. 2015. PMID: 25480923

4

Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.

Sajadian SO, Ehnert S, Vakilian H, Koutsouraki E, Damm G, Seehofer D, Thasler W, Dooley S, Baharvand H, Sipos B, Nussler AK. Sajadian SO, et al. Among authors: damm g. Clin Epigenetics. 2015 Sep 11;7(1):98. doi: 10.1186/s13148-015-0133-x. eCollection 2015. Clin Epigenetics. 2015. PMID: 26366235 Free PMC article.

5

Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI.

Kegel V, Pfeiffer E, Burkhardt B, Liu JL, Zeilinger K, Nüssler AK, Seehofer D, Damm G. Kegel V, et al. Among authors: damm g. Mediators Inflamm. 2015;2015:640631. doi: 10.1155/2015/640631. Epub 2015 Sep 28. Mediators Inflamm. 2015. PMID: 26491234 Free PMC article.

6

Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.

Herzog N, Hansen M, Miethbauer S, Schmidtke KU, Anderer U, Lupp A, Sperling S, Seehofer D, Damm G, Scheibner K, Küpper JH. Herzog N, et al. Among authors: damm g. Cell Biol Int. 2016 Mar;40(3):341-53. doi: 10.1002/cbin.10574. Epub 2016 Jan 18. Cell Biol Int. 2016. PMID: 26715207

7

Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation.

Iwamoto N, D'Alessandro LA, Depner S, Hahn B, Kramer BA, Lucarelli P, Vlasov A, Stepath M, Böhm ME, Deharde D, Damm G, Seehofer D, Lehmann WD, Klingmüller U, Schilling M. Iwamoto N, et al. Among authors: damm g. Sci Signal. 2016 Feb 2;9(413):ra13. doi: 10.1126/scisignal.aab1967. Sci Signal. 2016. PMID: 26838549

8

Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.

Kandel BA, Thomas M, Winter S, Damm G, Seehofer D, Burk O, Schwab M, Zanger UM. Kandel BA, et al. Among authors: damm g. Biochim Biophys Acta. 2016 Sep;1859(9):1218-1227. doi: 10.1016/j.bbagrm.2016.03.007. Epub 2016 Mar 17. Biochim Biophys Acta. 2016. PMID: 26994748

9

Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells.

Kegel V, Deharde D, Pfeiffer E, Zeilinger K, Seehofer D, Damm G. Kegel V, et al. Among authors: damm g. J Vis Exp. 2016 Mar 30;(109):e53069. doi: 10.3791/53069. J Vis Exp. 2016. PMID: 27077489 Free PMC article.

10

In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System.

Knöspel F, Jacobs F, Freyer N, Damm G, De Bondt A, van den Wyngaert I, Snoeys J, Monshouwer M, Richter M, Strahl N, Seehofer D, Zeilinger K. Knöspel F, et al. Among authors: damm g. Int J Mol Sci. 2016 Apr 16;17(4):584. doi: 10.3390/ijms17040584. Int J Mol Sci. 2016. PMID: 27092500 Free PMC article.

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