Danen E - Search Results

1

Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines.

Suijker J, Oosting J, Koornneef A, Struys EA, Salomons GS, Schaap FG, Waaijer CJ, Wijers-Koster PM, Briaire-de Bruijn IH, Haazen L, Riester SM, Dudakovic A, Danen E, Cleton-Jansen AM, van Wijnen AJ, Bovée JV. Suijker J, et al. Among authors: danen e. Oncotarget. 2015 May 20;6(14):12505-19. doi: 10.18632/oncotarget.3723. Oncotarget. 2015. PMID: 25895133 Free PMC article.

2

Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.

Carreras Puigvert J, von Stechow L, Siddappa R, Pines A, Bahjat M, Haazen LC, Olsen JV, Vrieling H, Meerman JH, Mullenders LH, van de Water B, Danen EH. Carreras Puigvert J, et al. Sci Signal. 2013 Jan 22;6(259):ra5. doi: 10.1126/scisignal.2003208. Sci Signal. 2013. PMID: 23354688

3

β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.

Truong HH, Xiong J, Ghotra VP, Nirmala E, Haazen L, Le Dévédec SE, Balcioğlu HE, He S, Snaar-Jagalska BE, Vreugdenhil E, Meerman JH, van de Water B, Danen EH. Truong HH, et al. Among authors: danen eh. Sci Signal. 2014 Feb 11;7(312):ra15. doi: 10.1126/scisignal.2004751. Sci Signal. 2014. PMID: 24518294

4

Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.

Baranski Z, Booij TH, Cleton-Jansen AM, Price LS, van de Water B, Bovée JV, Hogendoorn PC, Danen EH. Baranski Z, et al. J Pathol. 2015 Jul;236(3):348-59. doi: 10.1002/path.4528. Epub 2015 Mar 30. J Pathol. 2015. PMID: 25757065

5

Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin.

Baranski Z, de Jong Y, Ilkova T, Peterse EF, Cleton-Jansen AM, van de Water B, Hogendoorn PC, Bovée JV, Danen EH. Baranski Z, et al. Oncotarget. 2015 Nov 3;6(34):36113-25. doi: 10.18632/oncotarget.5333. Oncotarget. 2015. PMID: 26416351 Free PMC article.

6

MEK inhibition induces apoptosis in osteosarcoma cells with constitutive ERK1/2 phosphorylation.

Baranski Z, Booij TH, Kuijjer ML, de Jong Y, Cleton-Jansen AM, Price LS, van de Water B, Bovée JV, Hogendoorn PC, Danen EH. Baranski Z, et al. Genes Cancer. 2015 Nov;6(11-12):503-12. doi: 10.18632/genesandcancer.91. Genes Cancer. 2015. PMID: 26807203 Free PMC article.

7

Targeting survivin as a potential new treatment for chondrosarcoma of bone.

de Jong Y, van Oosterwijk JG, Kruisselbrink AB, Briaire-de Bruijn IH, Agrogiannis G, Baranski Z, Cleven AH, Cleton-Jansen AM, van de Water B, Danen EH, Bovée JV. de Jong Y, et al. Among authors: danen eh. Oncogenesis. 2016 May 9;5(5):e222. doi: 10.1038/oncsis.2016.33. Oncogenesis. 2016. PMID: 27159675 Free PMC article.

8

No preclinical rationale for IGF1R directed therapy in chondrosarcoma of bone.

Peterse EF, Cleven AH, De Jong Y, Briaire-de Bruijn I, Fletcher JA, Danen EH, Cleton-Jansen AM, Bovée JV. Peterse EF, et al. BMC Cancer. 2016 Jul 14;16:475. doi: 10.1186/s12885-016-2522-8. BMC Cancer. 2016. PMID: 27418340 Free PMC article.

9

NAD Synthesis Pathway Interference Is a Viable Therapeutic Strategy for Chondrosarcoma.

Peterse EFP, van den Akker BEWM, Niessen B, Oosting J, Suijker J, de Jong Y, Danen EHJ, Cleton-Jansen AM, Bovée JVMG. Peterse EFP, et al. Among authors: danen ehj. Mol Cancer Res. 2017 Dec;15(12):1714-1721. doi: 10.1158/1541-7786.MCR-17-0293. Epub 2017 Aug 31. Mol Cancer Res. 2017. PMID: 28860121

10

Inhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo- and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation Status.

Venneker S, Kruisselbrink AB, Briaire-de Bruijn IH, de Jong Y, van Wijnen AJ, Danen EHJ, Bovée JVMG. Venneker S, et al. Cancers (Basel). 2019 Dec 2;11(12):1918. doi: 10.3390/cancers11121918. Cancers (Basel). 2019. PMID: 31810230 Free PMC article.

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