Danenberg PV - Search Results

1

Effect of 5, 10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2'-deoxyuridylate from thymidylate synthetase: evidence for an ordered mechanism.

Danenberg PV, Danenberg KD. Danenberg PV, et al. Among authors: danenberg kd. Biochemistry. 1978 Sep 19;17(19):4018-24. doi: 10.1021/bi00612a022. Biochemistry. 1978. PMID: 101234 No abstract available.

2

Deoxyuridylate effects on thymidylate synthase-5-fluorodeoxyuridylate-folate ternary complex formation.

Spears CP, Hayes AA, Shahinian AH, Danenberg PV, Frösing R, Gustavsson BG. Spears CP, et al. Among authors: danenberg pv. Biochem Pharmacol. 1989 Sep 15;38(18):2985-93. doi: 10.1016/0006-2952(89)90006-3. Biochem Pharmacol. 1989. PMID: 2783153

3

Thymidylate synthetase: mechanism of inhibition by 5-fluoro-2'-deoxyuridylate.

Langenbach RJ, Danenberg PV, Heidelberger C. Langenbach RJ, et al. Among authors: danenberg pv. Biochem Biophys Res Commun. 1972 Sep 26;48(6):1565-71. doi: 10.1016/0006-291x(72)90892-3. Biochem Biophys Res Commun. 1972. PMID: 4263280 No abstract available.

4

Large-scale and small-scale methods for the preparation of 5,10-methylenetetrahydrofolate.

Zarow C, Pellino AM, Danenberg PV. Zarow C, et al. Among authors: danenberg pv. Prep Biochem. 1982;12(5):381-93. doi: 10.1080/10826068208070592. Prep Biochem. 1982. PMID: 6820505

5

Hydrodynamic behavior of human and bacterial thymidylate synthetases and thymidylate synthetase--5-fluoro-2'-deoxyuridylate--5,10-methylenetetrahydrofolate complexes. Evidence for large conformational changes during catalysis.

Lockshin A, Danenberg PV. Lockshin A, et al. Among authors: danenberg pv. Biochemistry. 1980 Sep 2;19(18):4244-51. doi: 10.1021/bi00559a016. Biochemistry. 1980. PMID: 6932226

6

Evidence from chemical degradation studies for a covalent bond from 5-fluoro-2'-deoxyuridylate to N-5 of tetrahydrofolate in the ternary complex of thymidylate synthetase-5-fluoro-2'-deoxyuridylate-5,10-methylenetetrahydrofolate.

Pellino AM, Danenberg PV. Pellino AM, et al. Among authors: danenberg pv. J Biol Chem. 1985 Sep 15;260(20):10996-1000. J Biol Chem. 1985. PMID: 3928628

7

Evidence for a sequential interaction of the subunits of thymidylate synthetase.

Danenberg KD, Danenberg PV. Danenberg KD, et al. Among authors: danenberg pv. J Biol Chem. 1979 Jun 10;254(11):4345-8. J Biol Chem. 1979. PMID: 108277 No abstract available.

8

Biochemical factors affecting the tightness of 5-fluorodeoxyuridylate binding to human thymidylate synthetase.

Lockshin A, Danenberg PV. Lockshin A, et al. Among authors: danenberg pv. Biochem Pharmacol. 1981 Feb 1;30(3):247-57. doi: 10.1016/0006-2952(81)90085-x. Biochem Pharmacol. 1981. PMID: 6939434 No abstract available.

9

Interaction of 5-ethynyl-2'-deoxyuridylate with thymidylate synthetase.

Danenberg PV, Bhatt RS, Kundu NG, Danenberg K, Heidelberger C. Danenberg PV, et al. Among authors: danenberg k. J Med Chem. 1981 Dec;24(12):1537-40. doi: 10.1021/jm00144a036. J Med Chem. 1981. PMID: 6796692

10

Thymidylate synthetase - substrate complex formation.

Danenberg PV, Lockshin A. Danenberg PV, et al. Mol Cell Biochem. 1982 Mar 5;43(1):49-57. doi: 10.1007/BF00229539. Mol Cell Biochem. 1982. PMID: 7078549

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